ID   A0A173MJX6_9BACT        Unreviewed;      1136 AA.
AC   A0A173MJX6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   SubName: Full=Alpha-1,2-mannosidase, putative {ECO:0000313|EMBL:SIT06965.1};
GN   ORFNames=SAMN05421788_103288 {ECO:0000313|EMBL:SIT06965.1};
OS   Filimonas lacunae.
OC   Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC   Filimonas.
OX   NCBI_TaxID=477680 {ECO:0000313|EMBL:SIT06965.1, ECO:0000313|Proteomes:UP000186917};
RN   [1] {ECO:0000313|Proteomes:UP000186917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21054 {ECO:0000313|Proteomes:UP000186917};
RA   Varghese N., Submissions S.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR   EMBL; FTOR01000003; SIT06965.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A173MJX6; -.
DR   STRING; 477680.SAMN05421788_103288; -.
DR   KEGG; fln:FLA_3974; -.
DR   OrthoDB; 9804511at2; -.
DR   Proteomes; UP000186917; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd00229; SGNH_hydrolase; 1.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR   Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR   Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR005887; GH92_a_mannosidase_put.
DR   InterPro; IPR041371; GH92_N.
DR   InterPro; IPR012939; Glyco_hydro_92.
DR   InterPro; IPR013830; SGNH_hydro.
DR   InterPro; IPR036514; SGNH_hydro_sf.
DR   NCBIfam; TIGR01180; aman2_put; 1.
DR   PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR   PANTHER; PTHR12143:SF39; SECRETED PROTEIN-RELATED; 1.
DR   Pfam; PF07971; Glyco_hydro_92; 1.
DR   Pfam; PF17678; Glyco_hydro_92N; 1.
DR   Pfam; PF13472; Lipase_GDSL_2; 1.
DR   SUPFAM; SSF52266; SGNH hydrolase; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186917};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..1136
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5030023069"
FT   DOMAIN          53..222
FT                   /note="SGNH hydrolase-type esterase"
FT                   /evidence="ECO:0000259|Pfam:PF13472"
FT   DOMAIN          404..649
FT                   /note="Glycosyl hydrolase family 92 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17678"
FT   DOMAIN          655..1116
FT                   /note="Glycosyl hydrolase family 92"
FT                   /evidence="ECO:0000259|Pfam:PF07971"
FT   REGION          485..504
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        487..504
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1136 AA;  127043 MW;  058CD090442A05E0 CRC64;
     MRNWCFIFLL WSGLAQAQAP LPVLPKDDFI TVRDGLPHFY QSLHTTHKAT IGFVGGSITY
     NPGWRNKLCA WLQQQYPQVQ FTFVTAAIPS LGSVAHVFRL QNDLLSTTRP DLVLVEAAVN
     DRGNGTDSIT QIRALDGIVR QIKQQNKFTD VVLMSFADPD KTNDYHHHKT PVEIANHEAV
     AAHYHLPSVN LGKEVHDRIQ HHELDWDRDI KDIHPSEYGQ QLYFQTIQHL LQVCLGKQPA
     RTMATIPAAM NKASFEAGYY YDITRAQTDN NWTLDKDWTP TDGLSTREGF VHVPMLTSAT
     PGATLQLPFQ GTAAGIAVTA GADAGTITYS IDNGPPQTLD LYTVHSSWLH LPSYYLLAGN
     LTNGKHVLHI TISQQTNTKS KGHACRIVHF LVNGPQLTKS ITDFVNPFIG TGAAGSGLSG
     NTFPGATVPF GMVQLSPDTR DVPDWGTASG YDYNDKTIAG FSHTHLSGTG VAELFDVLLM
     PITGPTSTEP GDASQPGSGY RSTFSHQQET ARPGYYQVKL LQYNINAELT ATTHAAFHRY
     TYPANSNSHV VIDLNHSLNK NSWNTRIIQS QLKLVNARTI EGYRIITGWA KLRKVYFHIE
     FSRPVTQHLF VDGNTTYYNN AVINGSNVRA ILDFDTPANS PLLVKVGLSS VSIANAQQNL
     QHEIAHWNFD QTTTQAKQLW QQELQKVAVE GTDKQKEIFY TALYHTFLQP NTLSDVNGSF
     MAANYTQQHT TGTHYSTFSL WDTYRAAHPL YTLLQPQRSA QFVKSMLSQY TTYGYLPVWQ
     LWGQENYCMI GNHAIPVITD AVLKGIPGID IQQAYEAVKN SSLIAHPNSP FAIWERYGYM
     PENIQTQSVS ITLEMAYDDW CVAQLAKKLG KTADYQRFLH RSQYYQNLYN HQTHFFQSKD
     DKGNWMAPFD PLKYGSNGGN PFTEGNAWQY YWYVPHDVPQ LITLTGGNQA FISKLDSFFT
     LSHNTEEINN NASGFIGQYA HGNEPSHHVA YLYNYAGQPW KTQYYVQKIM RELYNNGSSG
     YAGNDDCGEM SAWYVFSALG FYPVNPANGV YAIGSPLLAH AKLQLPGGKT FTIRTHTSSD
     NDIYIQSATL NGKPYTHTYI RHSDIMQGGT LEFTLGPQPA TSWGVLPDDK PIHNSF
//