ID   A0A173MNI3_9BACT        Unreviewed;       384 AA.
AC   A0A173MNI3;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=galactokinase {ECO:0000256|ARBA:ARBA00012315};
DE            EC=2.7.1.6 {ECO:0000256|ARBA:ARBA00012315};
DE   AltName: Full=Galactose kinase {ECO:0000256|ARBA:ARBA00029590};
GN   ORFNames=SAMN05421788_101644 {ECO:0000313|EMBL:SIS68883.1};
OS   Filimonas lacunae.
OC   Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC   Filimonas.
OX   NCBI_TaxID=477680 {ECO:0000313|EMBL:SIS68883.1, ECO:0000313|Proteomes:UP000186917};
RN   [1] {ECO:0000313|Proteomes:UP000186917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21054 {ECO:0000313|Proteomes:UP000186917};
RA   Varghese N., Submissions S.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Carbohydrate metabolism; galactose metabolism.
CC       {ECO:0000256|ARBA:ARBA00004947}.
CC   -!- SIMILARITY: Belongs to the GHMP kinase family. GalK subfamily.
CC       {ECO:0000256|ARBA:ARBA00006566}.
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DR   EMBL; FTOR01000001; SIS68883.1; -; Genomic_DNA.
DR   RefSeq; WP_076375585.1; NZ_FTOR01000001.1.
DR   AlphaFoldDB; A0A173MNI3; -.
DR   STRING; 477680.SAMN05421788_101644; -.
DR   KEGG; fln:FLA_5251; -.
DR   OrthoDB; 250531at2; -.
DR   Proteomes; UP000186917; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004335; F:galactokinase activity; IEA:InterPro.
DR   GO; GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.30.70.890; GHMP kinase, C-terminal domain; 1.
DR   InterPro; IPR000705; Galactokinase.
DR   InterPro; IPR019741; Galactokinase_CS.
DR   InterPro; IPR019539; GalKase_N.
DR   InterPro; IPR013750; GHMP_kinase_C_dom.
DR   InterPro; IPR036554; GHMP_kinase_C_sf.
DR   InterPro; IPR006204; GHMP_kinase_N_dom.
DR   InterPro; IPR006203; GHMP_knse_ATP-bd_CS.
DR   InterPro; IPR006206; Mevalonate/galactokinase.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR   NCBIfam; TIGR00131; gal_kin; 1.
DR   PANTHER; PTHR10457:SF35; GALACTOKINASE; 1.
DR   PANTHER; PTHR10457; MEVALONATE KINASE/GALACTOKINASE; 1.
DR   Pfam; PF10509; GalKase_gal_bdg; 1.
DR   Pfam; PF08544; GHMP_kinases_C; 1.
DR   Pfam; PF00288; GHMP_kinases_N; 1.
DR   PIRSF; PIRSF000530; Galactokinase; 1.
DR   PRINTS; PR00473; GALCTOKINASE.
DR   PRINTS; PR00959; MEVGALKINASE.
DR   SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR   PROSITE; PS00106; GALACTOKINASE; 1.
DR   PROSITE; PS00627; GHMP_KINASES_ATP; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Galactose metabolism {ECO:0000256|ARBA:ARBA00023144};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SIS68883.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186917};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          11..58
FT                   /note="Galactokinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10509"
FT   DOMAIN          112..177
FT                   /note="GHMP kinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00288"
FT   DOMAIN          281..362
FT                   /note="GHMP kinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08544"
SQ   SEQUENCE   384 AA;  42354 MW;  410205335E6D141D CRC64;
     MNNQVQQAKE VFEQKFGTTP VLFFSPGRIN LIGEHVDYNN GFVMPAAIDK GVVFAIAPNN
     TSNIRVYSID MKEDLEVALD QVAPKEGWAN YILGVVDQFQ KRGAAIKGFD VAFGGNLPAG
     AGLSSSAAVE CGLASGLNTI FNIGLNRVEI ALLSQKAEHT FPGVKCGIMD QFANMMGEKD
     HVLLLDCDTM EYKALPLQLQ GHVIMLINSK VHHSLASGEY NVRRQQCETG LAILQQLYPG
     TKTFRDITPE QVQQAEDKLD KDVFRRCLFV TQEIQRTQKA AALLQENKLP EFGQLMFATH
     EGLSKLYDVS CPELDFLVEQ AKEYKAILGS RLMGGGFGGC TINIVAESEA KEIGEKISEA
     YKKHFNITPE VYIMQTGNGT YEVK
//