UniProt: A0A173X5C2

Database: UniProt
Entry: A0A173X5C2_9FIRM

LinkDB:  A0A173X5C2_9FIRM 
Original site:  A0A173X5C2_9FIRM

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Ontology (1)   
   GO (1)   
Gene (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (14)   
   EMBL (14)   
Protein domain (2)   
   InterPro (1)   
   Pfam (1)   
Literature (1)   
   PubMed (1)   
All databases (20)   

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ID   A0A173X5C2_9FIRM        Unreviewed;       230 AA.
AC   A0A173X5C2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Inner membrane protein yohK {ECO:0000313|EMBL:CUN46911.1};
DE   SubName: Full=LrgB family protein {ECO:0000313|EMBL:RGN07140.1};
GN   Name=yohK {ECO:0000313|EMBL:CUN46911.1};
GN   ORFNames=DW021_03115 {ECO:0000313|EMBL:RHL49350.1}, DW040_01115
GN   {ECO:0000313|EMBL:RHK97937.1}, DW272_00380
GN   {ECO:0000313|EMBL:RHG19700.1}, DW767_02740
GN   {ECO:0000313|EMBL:RHE14715.1}, DW859_00785
GN   {ECO:0000313|EMBL:RHC09984.1}, DWW07_03165
GN   {ECO:0000313|EMBL:RGV65565.1}, DWX77_01110
GN   {ECO:0000313|EMBL:RGS75939.1}, DWY46_05180
GN   {ECO:0000313|EMBL:RGR50778.1}, DWZ12_09265
GN   {ECO:0000313|EMBL:RGQ04745.1}, DXB38_00680
GN   {ECO:0000313|EMBL:RGN90535.1}, DXB81_01010
GN   {ECO:0000313|EMBL:RGN07140.1}, EAI82_02980
GN   {ECO:0000313|EMBL:RYT68185.1}, ERS852394_00312
GN   {ECO:0000313|EMBL:CUN46911.1}, ERS852533_00064
GN   {ECO:0000313|EMBL:CUP03508.1};
OS   Blautia obeum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX   NCBI_TaxID=40520 {ECO:0000313|EMBL:CUN46911.1, ECO:0000313|Proteomes:UP000095409};
RN   [1] {ECO:0000313|Proteomes:UP000095409, ECO:0000313|Proteomes:UP000095413}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2789STDY5608837 {ECO:0000313|EMBL:CUN46911.1,
RC   ECO:0000313|Proteomes:UP000095409}, and 2789STDY5834921
RC   {ECO:0000313|EMBL:CUP03508.1, ECO:0000313|Proteomes:UP000095413};
RG   Pathogen Informatics;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000261105, ECO:0000313|Proteomes:UP000261222}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF14-23 {ECO:0000313|EMBL:RGV65565.1,
RC   ECO:0000313|Proteomes:UP000265828}, AF21-24
RC   {ECO:0000313|EMBL:RGS75939.1, ECO:0000313|Proteomes:UP000284242},
RC   AF25-21 {ECO:0000313|EMBL:RGR50778.1,
RC   ECO:0000313|Proteomes:UP000285839}, AF29-2BH
RC   {ECO:0000313|EMBL:RGQ04745.1, ECO:0000313|Proteomes:UP000283585},
RC   AF37-6AC {ECO:0000313|EMBL:RHL49350.1,
RC   ECO:0000313|Proteomes:UP000285897}, AF39-4
RC   {ECO:0000313|EMBL:RHK97937.1, ECO:0000313|Proteomes:UP000284267},
RC   AM22-9LB {ECO:0000313|EMBL:RHG19700.1,
RC   ECO:0000313|Proteomes:UP000284220}, AM29-25AC
RC   {ECO:0000313|EMBL:RHE14715.1, ECO:0000313|Proteomes:UP000284644},
RC   AM37-4AC {ECO:0000313|EMBL:RHC09984.1,
RC   ECO:0000313|Proteomes:UP000265808}, OM03-6
RC   {ECO:0000313|EMBL:RGN90535.1, ECO:0000313|Proteomes:UP000261105}, and
RC   OM06-11AA {ECO:0000313|EMBL:RGN07140.1,
RC   ECO:0000313|Proteomes:UP000261222};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:RYT68185.1, ECO:0000313|Proteomes:UP000293506}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Af_0058 {ECO:0000313|EMBL:RYT68185.1}, and af_0058
RC   {ECO:0000313|Proteomes:UP000293506};
RX   PubMed=30630933; DOI=.1126/science.aau5238;
RA   Jiang X., Hall A.B., Arthur T.D., Plichta D.R., Covington C.T., Poyet M.,
RA   Crothers J., Moses P.L., Tolonen A.C., Vlamakis H., Alm E.J., Xavier R.J.;
RT   "Invertible promoters mediate bacterial phase variation, antibiotic
RT   resistance, and host adaptation in the gut.";
RL   Science 363:181-187(2019).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CYZD01000001; CUN46911.1; -; Genomic_DNA.
DR   EMBL; CZBA01000001; CUP03508.1; -; Genomic_DNA.
DR   EMBL; QSUB01000001; RGN07140.1; -; Genomic_DNA.
DR   EMBL; QSUZ01000001; RGN90535.1; -; Genomic_DNA.
DR   EMBL; QRSS01000009; RGQ04745.1; -; Genomic_DNA.
DR   EMBL; QRUH01000002; RGR50778.1; -; Genomic_DNA.
DR   EMBL; QRVV01000002; RGS75939.1; -; Genomic_DNA.
DR   EMBL; QRZI01000002; RGV65565.1; -; Genomic_DNA.
DR   EMBL; QSHL01000001; RHC09984.1; -; Genomic_DNA.
DR   EMBL; QSJW01000002; RHE14715.1; -; Genomic_DNA.
DR   EMBL; QRHZ01000001; RHG19700.1; -; Genomic_DNA.
DR   EMBL; QROE01000001; RHK97937.1; -; Genomic_DNA.
DR   EMBL; QROS01000002; RHL49350.1; -; Genomic_DNA.
DR   EMBL; RCXQ01000002; RYT68185.1; -; Genomic_DNA.
DR   RefSeq; WP_005426018.1; NZ_WWVS01000002.1.
DR   AlphaFoldDB; A0A173X5C2; -.
DR   GeneID; 79804547; -.
DR   OrthoDB; 9811701at2; -.
DR   Proteomes; UP000095409; Unassembled WGS sequence.
DR   Proteomes; UP000095413; Unassembled WGS sequence.
DR   Proteomes; UP000261105; Unassembled WGS sequence.
DR   Proteomes; UP000261222; Unassembled WGS sequence.
DR   Proteomes; UP000265808; Unassembled WGS sequence.
DR   Proteomes; UP000265828; Unassembled WGS sequence.
DR   Proteomes; UP000283585; Unassembled WGS sequence.
DR   Proteomes; UP000284220; Unassembled WGS sequence.
DR   Proteomes; UP000284242; Unassembled WGS sequence.
DR   Proteomes; UP000284267; Unassembled WGS sequence.
DR   Proteomes; UP000284644; Unassembled WGS sequence.
DR   Proteomes; UP000285839; Unassembled WGS sequence.
DR   Proteomes; UP000285897; Unassembled WGS sequence.
DR   Proteomes; UP000293506; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007300; CidB/LrgB.
DR   PANTHER; PTHR30249:SF0; PLASTIDAL GLYCOLATE_GLYCERATE TRANSLOCATOR 1, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR30249; PUTATIVE SEROTONIN TRANSPORTER; 1.
DR   Pfam; PF04172; LrgB; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095409};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        92..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        144..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        206..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   230 AA;  24360 MW;  B0EF46DAA4616566 CRC64;
     MDNLILSSAT VGIVISLLAY EIGLAAQRKW KLAVLNPLLI SIILVIAFLV VFHVDYESYN
     MSAKYLSYLL TPATVCLAIP LYLQLDLLKK NIVAILVGVF SGVLASLGTV LAMSVVFGLN
     HKEYVTMLPK SITTAIGMGV SEELGGYVTI SVAVIIITGV LGNMAAEFIC KLFRIKSPIS
     RGLAIGTASH AVGTARAMEL GEVEGAMSSL AIVVCGLCTV IGASIFSYLW
//

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