ID A0A173X8E4_9FIRM Unreviewed; 577 AA.
AC A0A173X8E4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI {ECO:0000313|EMBL:CUN47540.1};
DE EC=3.6.3.- {ECO:0000313|EMBL:CUN47540.1};
GN Name=yheI_1 {ECO:0000313|EMBL:CUN47540.1};
GN ORFNames=ERS852394_00327 {ECO:0000313|EMBL:CUN47540.1};
OS Blautia obeum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=40520 {ECO:0000313|EMBL:CUN47540.1, ECO:0000313|Proteomes:UP000095409};
RN [1] {ECO:0000313|EMBL:CUN47540.1, ECO:0000313|Proteomes:UP000095409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5608837 {ECO:0000313|EMBL:CUN47540.1,
RC ECO:0000313|Proteomes:UP000095409};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CYZD01000001; CUN47540.1; -; Genomic_DNA.
DR RefSeq; WP_055065503.1; NZ_JAAIPR010000001.1.
DR AlphaFoldDB; A0A173X8E4; -.
DR Proteomes; UP000095409; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18548; ABC_6TM_Tm287_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF276; ABC TRANSPORTER, ATP-BINDING_PERMEASE PROTEIN; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:CUN47540.1};
KW Hydrolase {ECO:0000313|EMBL:CUN47540.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000095409};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..298
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 332..568
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 577 AA; 64046 MW; 2B1F490D3EA8AECC CRC64;
MNKTLFKSIR EYKKQSLLAP FLVILEVLME VLIPLEMAKI IDVGIANGDL GYIVQRGIIL
VAMAMLALFF GVQAGNMAAV AAAGYAKNLR HDIFYKVQDF SFKNIDHFST SGLVTRMTTD
ITNVQMAYMM SIRLLARAPI MILLSWIMTL LINVKIALLF LIVIPLLGGT LMFIAKKAHP
HFIRVFDEYD ELNNSVQENV NASRVVKAFV REDYEINKFH GVSNYVYTLF TKAEKIVAWN
SPVLQFMMYA VVLLIALIGG RSIVFGTMET GELTSVIVYA IQILMSLNMV TFVFVMIMIA
GASTDRITEV LNEVPEMQDK ADAVKEVRNG EITFEHVDFS YAGEGGNLSL KDINLHIKSG
QTVGIIGGTG SAKSTLVQMI PRLYDVTGGA VKVAGVDVRD YNLEVLRDQV SMVLQKNVLF
SGTIYDNIRW GNEHASDEEV KRVCRLAQAD GFVNEFPNGY ETMIVQGGNN VSGGQKQRLC
IARALLKKPK ILILDDSTSA VDTKTDALIR KAFREEIPDT TKIIIAQRVS SIEDADQIIV
LDDGKIAGVG TSEELLQTNE IYREVYESQV KGGEEDE
//
