ID A0A174CSD1_9CLOT Unreviewed; 201 AA.
AC A0A174CSD1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family {ECO:0000313|EMBL:CUO16083.1};
DE EC=2.3.1.89 {ECO:0000313|EMBL:CUO16083.1};
GN Name=dapH_2 {ECO:0000313|EMBL:CUO16083.1};
GN ORFNames=ERS852407_02017 {ECO:0000313|EMBL:CUO16083.1};
OS Hungatella hathewayi.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX NCBI_TaxID=154046 {ECO:0000313|EMBL:CUO16083.1, ECO:0000313|Proteomes:UP000095651};
RN [1] {ECO:0000313|EMBL:CUO16083.1, ECO:0000313|Proteomes:UP000095651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5608850 {ECO:0000313|EMBL:CUO16083.1,
RC ECO:0000313|Proteomes:UP000095651};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CYZE01000004; CUO16083.1; -; Genomic_DNA.
DR RefSeq; WP_055654682.1; NZ_CYZE01000004.1.
DR AlphaFoldDB; A0A174CSD1; -.
DR Proteomes; UP000095651; Unassembled WGS sequence.
DR GO; GO:0047200; F:tetrahydrodipicolinate N-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd03360; LbH_AT_putative; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR020019; AcTrfase_PglD-like.
DR InterPro; IPR041561; PglD_N.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR03570; NeuD_NnaD; 1.
DR PANTHER; PTHR43300; ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43300:SF7; UDP-N-ACETYLBACILLOSAMINE N-ACETYLTRANSFERASE; 1.
DR Pfam; PF17836; PglD_N; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:CUO16083.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000095651};
KW Transferase {ECO:0000313|EMBL:CUO16083.1}.
FT DOMAIN 3..77
FT /note="PglD N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17836"
FT ACT_SITE 130
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
FT BINDING 10..12
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 32..33
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 65
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 139
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 160
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT SITE 131
FT /note="Increases basicity of active site His"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
SQ SEQUENCE 201 AA; 21395 MW; 9F918389F11EB996 CRC64;
MRKLVIIGAS GHGKVVADIA EKNEYKNIVF LDDSELAECA GFPVVGRSTD AWLYKETSEF
VIAIGKADIR QKIQESLKGY EFAVLVHPNA SVSRNVEIGK GTVVMAGAVI NSNSVVGRGC
IINTGASIDH DDKIGDYVHI SVGAHIAGSV TVGSRTWLGI GSCVINNLHI CSDCMIGAGS
VVIRDINERG TYVGNPARRI R
//
