ID   A0A174F878_9CLOT        Unreviewed;       601 AA.
AC   A0A174F878;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Integral membrane sensor signal transduction histidine kinase {ECO:0000313|EMBL:CUO44530.1};
GN   Name=ypdA_21 {ECO:0000313|EMBL:CUO44530.1};
GN   ORFNames=ERS852407_02849 {ECO:0000313|EMBL:CUO44530.1};
OS   Hungatella hathewayi.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX   NCBI_TaxID=154046 {ECO:0000313|EMBL:CUO44530.1, ECO:0000313|Proteomes:UP000095651};
RN   [1] {ECO:0000313|EMBL:CUO44530.1, ECO:0000313|Proteomes:UP000095651}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2789STDY5608850 {ECO:0000313|EMBL:CUO44530.1,
RC   ECO:0000313|Proteomes:UP000095651};
RG   Pathogen Informatics;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CYZE01000006; CUO44530.1; -; Genomic_DNA.
DR   RefSeq; WP_055656048.1; NZ_CYZE01000006.1.
DR   AlphaFoldDB; A0A174F878; -.
DR   Proteomes; UP000095651; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:CUO44530.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095651};
KW   Transferase {ECO:0000313|EMBL:CUO44530.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        292..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          379..458
FT                   /note="Signal transduction histidine kinase internal
FT                   region"
FT                   /evidence="ECO:0000259|Pfam:PF06580"
FT   DOMAIN          477..555
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|Pfam:PF02518"
SQ   SEQUENCE   601 AA;  68438 MW;  BCCA000163337B14 CRC64;
     MSGQILQKLS IKKKIQLIIL FGILIVSLTA FICIHFISQS YEKLLYQSVS NSLSYSAGNI
     SDKIDNIDLL SGLILSDQAI QDYLVNIETT DSPSELDSSC SQLYRSLINY LFSFDNSNIA
     NISIQITPEL SVSTSSYKQQ KLPEAVTNAL VTQALEADGV NLWVTDYCDE YGFFLVRELK
     QTYALKLDTL GVLMINVDSN KMVEDAISYN SANDNLYLLL DENHTIYQSP QLLKADKERL
     RNLPSGYQIL SLNKQTMFAV RDTIIDLGWD YISLVPYNSI IDTARFTKSI CLIVIILCLI
     LTFFISTGLL TTLTYHIDLL IRRMKRFEDG SYEADPHRTE YQRREDEIGM LHQSFDSMAK
     KIDTLINENY KNEILKRDAQ IKAMENQINP HFLYNTLDAI NWRSIAIGAE DITKITLSLG
     SLLRITLQNS EDSYTIAKEV KVLENYITIQ KLRYGERLDY HLTIPDEYMA CEIPKLTLQP
     LLENAVHYGL EENSEICHIV ITARRDQKDL LIEVKNNGSA FEEDLLEKIE SGKLQPKGHG
     IGLVNISRRL ELTYGPAYHL KLYNDIDLTI GEEYAIAQVR LPLSRIQKGE FANAEVTDCG
     R
//