ID A0A174FU58_9CLOT Unreviewed; 395 AA.
AC A0A174FU58;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Trypsin domain-containing protein {ECO:0000313|EMBL:CUO53794.1};
GN Name=hhoB {ECO:0000313|EMBL:CUO53794.1};
GN ORFNames=ERS852471_01752 {ECO:0000313|EMBL:CUO53794.1};
OS Clostridium disporicum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=84024 {ECO:0000313|EMBL:CUO53794.1, ECO:0000313|Proteomes:UP000095594};
RN [1] {ECO:0000313|EMBL:CUO53794.1, ECO:0000313|Proteomes:UP000095594}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5834856 {ECO:0000313|EMBL:CUO53794.1,
RC ECO:0000313|Proteomes:UP000095594};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
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DR EMBL; CYZX01000010; CUO53794.1; -; Genomic_DNA.
DR RefSeq; WP_055265705.1; NZ_CYZX01000010.1.
DR AlphaFoldDB; A0A174FU58; -.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000095594; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000095594};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 305..383
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 17..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 395 AA; 42300 MW; D4652EBCB75A5AEE CRC64;
MDNENIYDAV YKEENLNQKN ENNSYNSERI RKPRKKGGGM GKIIALVVSC SLLGGVAGSG
LTYVMMNNEV DTTQQNTVSN VNTADVSFKN DSTLSITEAF EKVAPAVVTV STKGVTSNGF
FQQQYEGVGS GFIINEDGYI LTNYHVIEGA SEISVTLSDN TTVAAKVVNY DENQDVAMLK
ITDSDVKIPA VVELGDSDQL RQGESVIAIG TPLSTNLSQT VTNGIVSALN RNVETESGVM
QNLIQTDASI NPGNSGGPLV NTRGQVVGIN TMKATGTDTE GIGFAIPIND ISDKIESLSK
PILNLGISIR TVDETLANKL SMEQGLYVVE VNEFSPAEKA GVKPGDLIVK VDGQRVKTFD
ELKEIKNSKN DGDTITLEVI RDGKTKTLDV TLTSE
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