ID A0A174GMS3_9FIRM Unreviewed; 419 AA.
AC A0A174GMS3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Carboxynorspermidine synthase {ECO:0000313|EMBL:VUX13740.1};
DE EC=1.5.1.43 {ECO:0000313|EMBL:VUX13740.1};
DE SubName: Full=Homospermidine synthase {ECO:0000313|EMBL:CUO63952.1};
DE SubName: Full=Saccharopine dehydrogenase family protein {ECO:0000313|EMBL:RGN87050.1};
GN ORFNames=DW272_16555 {ECO:0000313|EMBL:RHG13582.1}, DW723_08285
GN {ECO:0000313|EMBL:RHE75673.1}, DW767_13245
GN {ECO:0000313|EMBL:RHE10875.1}, DW859_11795
GN {ECO:0000313|EMBL:RHC05242.1}, DWX77_06925
GN {ECO:0000313|EMBL:RGS74668.1}, DWY46_09570
GN {ECO:0000313|EMBL:RGR49207.1}, DWZ12_12525
GN {ECO:0000313|EMBL:RGQ03505.1}, DXB38_10865
GN {ECO:0000313|EMBL:RGN87050.1}, EAI82_10015
GN {ECO:0000313|EMBL:RYT66552.1}, ERS852394_02649
GN {ECO:0000313|EMBL:CUO63952.1}, ROSSTS7063_02273
GN {ECO:0000313|EMBL:VUX13740.1};
OS Blautia obeum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=40520 {ECO:0000313|EMBL:CUO63952.1, ECO:0000313|Proteomes:UP000095409};
RN [1] {ECO:0000313|EMBL:CUO63952.1, ECO:0000313|Proteomes:UP000095409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5608837 {ECO:0000313|EMBL:CUO63952.1,
RC ECO:0000313|Proteomes:UP000095409};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000261105, ECO:0000313|Proteomes:UP000265808}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF21-24 {ECO:0000313|EMBL:RGS74668.1,
RC ECO:0000313|Proteomes:UP000284242}, AF25-21
RC {ECO:0000313|EMBL:RGR49207.1, ECO:0000313|Proteomes:UP000285839},
RC AF29-2BH {ECO:0000313|EMBL:RGQ03505.1,
RC ECO:0000313|Proteomes:UP000283585}, AM22-9LB
RC {ECO:0000313|EMBL:RHG13582.1, ECO:0000313|Proteomes:UP000284220},
RC AM27-32LB {ECO:0000313|EMBL:RHE75673.1,
RC ECO:0000313|Proteomes:UP000283928}, AM29-25AC
RC {ECO:0000313|EMBL:RHE10875.1, ECO:0000313|Proteomes:UP000284644},
RC AM37-4AC {ECO:0000313|EMBL:RHC05242.1,
RC ECO:0000313|Proteomes:UP000265808}, and OM03-6
RC {ECO:0000313|EMBL:RGN87050.1, ECO:0000313|Proteomes:UP000261105};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:RYT66552.1, ECO:0000313|Proteomes:UP000293506}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=af_0058 {ECO:0000313|Proteomes:UP000293506}, and Af_0058
RC {ECO:0000313|EMBL:RYT66552.1};
RX PubMed=30630933; DOI=.1126/science.aau5238;
RA Jiang X., Hall A.B., Arthur T.D., Plichta D.R., Covington C.T., Poyet M.,
RA Crothers J., Moses P.L., Tolonen A.C., Vlamakis H., Alm E.J., Xavier R.J.;
RT "Invertible promoters mediate bacterial phase variation, antibiotic
RT resistance, and host adaptation in the gut.";
RL Science 363:181-187(2019).
RN [4] {ECO:0000313|EMBL:VUX13740.1, ECO:0000313|Proteomes:UP000409147}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ruminococcus_obeum_SSTS_Bg7063 {ECO:0000313|EMBL:VUX13740.1};
RA Hibberd C M., Gehrig L. J., Chang H.-W., Venkatesh S.;
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CYZD01000017; CUO63952.1; -; Genomic_DNA.
DR EMBL; QSUZ01000014; RGN87050.1; -; Genomic_DNA.
DR EMBL; QRSS01000016; RGQ03505.1; -; Genomic_DNA.
DR EMBL; QRUH01000006; RGR49207.1; -; Genomic_DNA.
DR EMBL; QRVV01000014; RGS74668.1; -; Genomic_DNA.
DR EMBL; QSHL01000008; RHC05242.1; -; Genomic_DNA.
DR EMBL; QSJW01000008; RHE10875.1; -; Genomic_DNA.
DR EMBL; QSKO01000009; RHE75673.1; -; Genomic_DNA.
DR EMBL; QRHZ01000016; RHG13582.1; -; Genomic_DNA.
DR EMBL; RCXQ01000008; RYT66552.1; -; Genomic_DNA.
DR EMBL; CABHNB010000032; VUX13740.1; -; Genomic_DNA.
DR RefSeq; WP_005424872.1; NZ_WWVS01000008.1.
DR AlphaFoldDB; A0A174GMS3; -.
DR GeneID; 79805539; -.
DR Proteomes; UP000095409; Unassembled WGS sequence.
DR Proteomes; UP000261105; Unassembled WGS sequence.
DR Proteomes; UP000265808; Unassembled WGS sequence.
DR Proteomes; UP000283585; Unassembled WGS sequence.
DR Proteomes; UP000283928; Unassembled WGS sequence.
DR Proteomes; UP000284220; Unassembled WGS sequence.
DR Proteomes; UP000284242; Unassembled WGS sequence.
DR Proteomes; UP000284644; Unassembled WGS sequence.
DR Proteomes; UP000285839; Unassembled WGS sequence.
DR Proteomes; UP000293506; Unassembled WGS sequence.
DR Proteomes; UP000409147; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR43796; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR PANTHER; PTHR43796:SF2; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:VUX13740.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000095409}.
FT DOMAIN 4..156
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 160..407
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 419 AA; 47264 MW; 72E9CD29CF419D88 CRC64;
MSRVLVIGCG GVASVAIQKC CQVDEVFTEM CIASRTKEKC DALVEKLKGK TKTVLTTAKV
DADDVDQLIE LINSYKPDLV MNIALPYQDL TIMDACLACG VNYMDTANYE PEDTDDPEWR
AIYEKRCKEE GFSAYFDYSW QWAYRKKFED AGLTALLGCG FDPGVTQAYC AYALKHEFDQ
IDTIDILDCN GGDHGYAFAT NFNPEINLRE VSAPGSYWEN GHWVEIPPMD IKREYNFDQV
GDKDMYLLHH EEIESLAKTI PGVKRIRFFM TFGQSYLDHM RCLEDVGMLS TTPIQYNGQE
IVPIQFLKAL LPDPASLGPR TKGKTNIGCI FTGVKDGKEK TYYIYNVCDH QECYHEVGSQ
AISYTTGVPA MCGALMMLTG KWIRPGVYTV EEFDPDPFLD ALDRYGLPRS ESHDPKLVD
//
