ID A0A174HH84_9CLOT Unreviewed; 608 AA.
AC A0A174HH84;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=DNA mismatch repair protein MutS domain-containing protein {ECO:0000313|EMBL:CUO72265.1};
GN Name=mutS2_1 {ECO:0000313|EMBL:CUO72265.1};
GN ORFNames=ERS852407_03723 {ECO:0000313|EMBL:CUO72265.1};
OS Hungatella hathewayi.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX NCBI_TaxID=154046 {ECO:0000313|EMBL:CUO72265.1, ECO:0000313|Proteomes:UP000095651};
RN [1] {ECO:0000313|EMBL:CUO72265.1, ECO:0000313|Proteomes:UP000095651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5608850 {ECO:0000313|EMBL:CUO72265.1,
RC ECO:0000313|Proteomes:UP000095651};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CYZE01000010; CUO72265.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A174HH84; -.
DR Proteomes; UP000095651; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR005747; MutS2.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF14; DNA MISMATCH REPAIR PROTEIN MUTS, TYPE 2; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005814; MutS_YshD; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000095651}.
FT DOMAIN 370..386
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 608 AA; 67995 MW; F5968D1CBB17AEEE CRC64;
MEPYLYEGDV RKSQKDTTEA RRIIESAGMP PIASMSDVDD ILIIVGQDGC LSAEQLESVG
MTLTAVKRLK DFLNRCRYLN TSLACYDEEL DPLEHLREQL AEAVRGGRVE DGASRLLRSL
RQDKIRMEEK VRAKADSILK SRKNCFADHY VTNRNGKMCL PVKKEYRSSV PGSVIDKSAT
GATLFIEPEA VASMNSELEL LKMEEENETR RILYELTAMV AENREVFEAD KRLIEKLDYI
FAKGKLSAAM EAKEPQINME RNIRIRNGRH PLMSREHAVP LSFELGDRGN GVVITGPNTG
GKTVTMKTVG VFCIMAQCGL HVPCEEASLC MNNQVLCDIG DGQNISENLS TFSAHITNVL
DILKKAGPES LVLLDELGSG TDPAEGMGIA IAILESLRQC GCLFLVTTHY PEVKGYAEAA
DGVENARMAF DRETLQPLYQ LVQGEAGESC ALFIAKKLGM PDAMLLRAEQ AAYGNLKPER
LQAESGGKKK KHVILPEGPR IRKQKEEKGI QKELAVKFTV GDSVLVLPDK KTGIVCRTVN
EKGVLQVQLH DRKIWINHKR IKLLVAAEEL YPEDYDFSII FDTVENRKNR HQMERKHQEG
VEIRMEDE
//
