ID A0A174J2R7_9CLOT Unreviewed; 429 AA.
AC A0A174J2R7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Citrate/sodium symporter {ECO:0000313|EMBL:CUO91868.1};
GN Name=citN {ECO:0000313|EMBL:CUO91868.1};
GN ORFNames=ERS852407_04398 {ECO:0000313|EMBL:CUO91868.1};
OS Hungatella hathewayi.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX NCBI_TaxID=154046 {ECO:0000313|EMBL:CUO91868.1, ECO:0000313|Proteomes:UP000095651};
RN [1] {ECO:0000313|EMBL:CUO91868.1, ECO:0000313|Proteomes:UP000095651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5608850 {ECO:0000313|EMBL:CUO91868.1,
RC ECO:0000313|Proteomes:UP000095651};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005348}.
CC -!- SIMILARITY: Belongs to the sodium:citrate (SCF) symporter family.
CC {ECO:0000256|PIRNR:PIRNR005348}.
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DR EMBL; CYZE01000014; CUO91868.1; -; Genomic_DNA.
DR RefSeq; WP_055658378.1; NZ_CYZE01000014.1.
DR AlphaFoldDB; A0A174J2R7; -.
DR Proteomes; UP000095651; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008514; F:organic anion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR004679; 2-OHcarboxylate_transport.
DR PANTHER; PTHR40033:SF1; CITRATE-SODIUM SYMPORTER; 1.
DR PANTHER; PTHR40033; NA(+)-MALATE SYMPORTER; 1.
DR Pfam; PF03390; 2HCT; 1.
DR PIRSF; PIRSF005348; YxkH; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|PIRNR:PIRNR005348};
KW Membrane {ECO:0000256|PIRNR:PIRNR005348, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000095651};
KW Symport {ECO:0000256|PIRNR:PIRNR005348};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|PIRNR:PIRNR005348}.
FT TRANSMEM 30..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 429 AA; 45515 MW; 305B747D459383FC CRC64;
MKLKNLGWLA FAIGLVTVIP LTLTEKLPGD LMGCFALMFV LGIVFGEIGD RVKFIHDWMG
GGPILCVFGP ALLMYFGILP AGLKDIMKNF MDNINFFAFF ISIMIAGAIL SLSRKIIIKS
TLKFLPAILG GLLMSCLLAF LVGAVTGYGG KNALFNLAIP IMGGGVGAGA LPLSQIYSGH
FGGESETILS VLMPAVVLGN VASIILGGIL NRVGKKKPTL TGNGQILKIA DPELARELEE
EDKEINGAPI TYEGLGAGFY VAMIAYMAAL IVNKFVYSGL HTYVYLIIIL TLVKAFGLLP
KHLEVGTIQW SRTWTKNLLY AALIPIGISN IDIGKTIEAL TNPIYLVLVL VIVIGAAIGA
GLVGHFMGLY EVEAAIAAGL CMSNMAQTGD LATLAAADRM ELLPYSSYSS RIGGSVVLVL
AGILLNFIH
//
