ID A0A174JCA1_9CLOT Unreviewed; 758 AA.
AC A0A174JCA1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=UvrD/REP helicase {ECO:0000313|EMBL:CUO95258.1};
DE EC=3.6.4.12 {ECO:0000313|EMBL:CUO95258.1};
GN Name=helD {ECO:0000313|EMBL:CUO95258.1};
GN ORFNames=ERS852471_02682 {ECO:0000313|EMBL:CUO95258.1};
OS Clostridium disporicum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=84024 {ECO:0000313|EMBL:CUO95258.1, ECO:0000313|Proteomes:UP000095594};
RN [1] {ECO:0000313|EMBL:CUO95258.1, ECO:0000313|Proteomes:UP000095594}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5834856 {ECO:0000313|EMBL:CUO95258.1,
RC ECO:0000313|Proteomes:UP000095594};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CYZX01000020; CUO95258.1; -; Genomic_DNA.
DR RefSeq; WP_055267352.1; NZ_CYZX01000020.1.
DR AlphaFoldDB; A0A174JCA1; -.
DR OrthoDB; 9787585at2; -.
DR Proteomes; UP000095594; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR048228; HelD_bacillota.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR NCBIfam; NF041464; HelD_BACSU; 1.
DR PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000095594}.
FT DOMAIN 198..597
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 219..226
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 758 AA; 87787 MW; 833AA1E4D2272FEA CRC64;
MDDLSRAKQV LKEKKELILY EINEKLKYEQ EIETKLKALT KAAKGNYDQE KENTEKIYNV
LKMDIESYEE AIKTPYFARV DFTEKLGALE KIYIGKQGIS SSKDGEEIVV DWRAPVADLY
YSGTGGEAYY KAPSGVIEGE LSLKRRFLYK NDDIERIFDE GINELFISGE EGVDLVDEFL
KINLEESKGK KLKEVVATIQ KEQNDIIRWP KNLPIIVQGS AGSGKTTIAL HRLAYLLYRY
RESMEGKDIL VLAPNKIFLD YISEILPSLG SKDVAQTTFQ DLVVKELKLK GKIRSKDDKL
KDIIETEDET LRKFMVNSSK VKGNLIFKTI IDRYIALLDS SSLEIEDIVI SGYTLFSKRE
ITRLYLKDLK VYPINKRKDE IKRYLNLKLK EKIQTLLLTV DREWDLKIRE VKSNSEDSEE
RRSELRKLYD ERDSIKNYIK QDSKKVMNEY FKNWRGITSK DIYLNMFKDK AVFDIAVDNR
IPFQLLEYMK EEVVENFEKG IVDEDDLAAL LYIHILLEGI EEKSKFKHIV IDEAQDYSPL
QIEVITNLTR GNSLTLVGDL AQGIYYYKGI KRWEDITEKI FNGNATYISL TQSYRSTVEI
IDFAQKALEA QNLGLTPAKP VLRHGDKPII KMSKDKKESA KFIEQIIEEI EGKGKRSIGI
ITRTLEEAKA LEKNIKKYCN RKIQLIKGNE KDSPEDVVII PSYLTKGLEF DGTIIYNPLE
SNYNDNLLNQ RLLYVALTRA LHYQYVIAEG EISRNIEY
//
