ID A0A174Q6U5_9BACE Unreviewed; 402 AA.
AC A0A174Q6U5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Putative ROK family transcriptional repressor protein {ECO:0000313|EMBL:CUP67536.1};
DE SubName: Full=ROK family transcriptional regulator {ECO:0000313|EMBL:KAA5464642.1};
GN Name=mlc {ECO:0000313|EMBL:CUP67536.1};
GN ORFNames=DW190_15230 {ECO:0000313|EMBL:RHH87670.1}, DW794_02185
GN {ECO:0000313|EMBL:RHD53348.1}, DWY26_02765
GN {ECO:0000313|EMBL:RGR73692.1}, DXA49_01505
GN {ECO:0000313|EMBL:RGY29485.1}, ERS852494_01092
GN {ECO:0000313|EMBL:CUO91861.1}, ERS852558_00753
GN {ECO:0000313|EMBL:CUP67536.1}, F2Y31_06050
GN {ECO:0000313|EMBL:KAA5501698.1}, F2Y35_05830
GN {ECO:0000313|EMBL:KAA5493691.1}, F2Y36_05925
GN {ECO:0000313|EMBL:KAA5464642.1}, F2Y39_04605
GN {ECO:0000313|EMBL:KAA5479894.1}, NXW23_12005
GN {ECO:0000313|EMBL:UVQ95146.1};
OS Bacteroides caccae.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=47678 {ECO:0000313|EMBL:CUP67536.1, ECO:0000313|Proteomes:UP000095725};
RN [1] {ECO:0000313|Proteomes:UP000095657, ECO:0000313|Proteomes:UP000095725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5834880 {ECO:0000313|EMBL:CUO91861.1,
RC ECO:0000313|Proteomes:UP000095657}, and 2789STDY5834946
RC {ECO:0000313|EMBL:CUP67536.1, ECO:0000313|Proteomes:UP000095725};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000283512, ECO:0000313|Proteomes:UP000284205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF24-29LB {ECO:0000313|EMBL:RGR73692.1,
RC ECO:0000313|Proteomes:UP000284205}, AM16-49B
RC {ECO:0000313|EMBL:RHH87670.1, ECO:0000313|Proteomes:UP000283512},
RC AM31-16AC {ECO:0000313|EMBL:RHD53348.1,
RC ECO:0000313|Proteomes:UP000284689}, and OF02-6LB
RC {ECO:0000313|EMBL:RGY29485.1, ECO:0000313|Proteomes:UP000284431};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000368418, ECO:0000313|Proteomes:UP000427825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A19 {ECO:0000313|EMBL:KAA5501698.1,
RC ECO:0000313|Proteomes:UP000368418}, BIOML-A21
RC {ECO:0000313|EMBL:KAA5493691.1, ECO:0000313|Proteomes:UP000491168},
RC BIOML-A25 {ECO:0000313|EMBL:KAA5479894.1,
RC ECO:0000313|Proteomes:UP000427825}, and BIOML-A31
RC {ECO:0000313|EMBL:KAA5464642.1, ECO:0000313|Proteomes:UP000475905};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
RN [4] {ECO:0000313|EMBL:UVQ95146.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BFG-474 {ECO:0000313|EMBL:UVQ95146.1};
RA Tisza M.J., Smith D., Dekker J.P.;
RT "Genome Sequencing of Bacteroides fragilis Group Isolates with Nanopore
RT Technology.";
RL Submitted (AUG-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CZAI01000002; CUO91861.1; -; Genomic_DNA.
DR EMBL; CZBL01000002; CUP67536.1; -; Genomic_DNA.
DR EMBL; VVYP01000005; KAA5464642.1; -; Genomic_DNA.
DR EMBL; VVYJ01000002; KAA5479894.1; -; Genomic_DNA.
DR EMBL; VVYF01000005; KAA5493691.1; -; Genomic_DNA.
DR EMBL; VVYD01000003; KAA5501698.1; -; Genomic_DNA.
DR EMBL; QRUO01000002; RGR73692.1; -; Genomic_DNA.
DR EMBL; QSCS01000002; RGY29485.1; -; Genomic_DNA.
DR EMBL; QSJD01000002; RHD53348.1; -; Genomic_DNA.
DR EMBL; QRKD01000016; RHH87670.1; -; Genomic_DNA.
DR EMBL; CP103166; UVQ95146.1; -; Genomic_DNA.
DR RefSeq; WP_005676463.1; NZ_WQQZ01000013.1.
DR STRING; 47678.ERS852494_01092; -.
DR GeneID; 75113996; -.
DR KEGG; bcac:CGC64_11130; -.
DR Proteomes; UP000095657; Unassembled WGS sequence.
DR Proteomes; UP000095725; Unassembled WGS sequence.
DR Proteomes; UP000283512; Unassembled WGS sequence.
DR Proteomes; UP000284205; Unassembled WGS sequence.
DR Proteomes; UP000284431; Unassembled WGS sequence.
DR Proteomes; UP000284689; Unassembled WGS sequence.
DR Proteomes; UP000368418; Unassembled WGS sequence.
DR Proteomes; UP000427825; Unassembled WGS sequence.
DR Proteomes; UP000475905; Unassembled WGS sequence.
DR Proteomes; UP000491168; Unassembled WGS sequence.
DR Proteomes; UP001060260; Chromosome.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01125; ROK; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000095657}.
SQ SEQUENCE 402 AA; 44544 MW; 1FBF10C667E756AE CRC64;
MKQHLLKEIE VGTKNALLKK KIITHYIYNG SSTITDLAKE LDLSVPTVTK FISEMCEEGY
INDYGKLETS GGRYPSLYGL NPESGYFIGV DIKKFAINIG LINFKGDMVE LKMNIPFKSE
NTSEALEELC KLILQFIKKV DIDNDKILNI NINVSGRVNP ESGYSFSQFN FEERPLAEVL
TEKIGFRVTI DNDTRAMTYG EYMKGCVKGE KDIIFVNVSW GLGIGIIIDG KIYTGKSGFS
GEFGHTNVFD NEIICHCGKK GCLETEASGS ALHRILIERI QNGESSILSN RILSKDNVLT
LDEIIASVNK EDLLCIEIVE EIGQKLGKQI AGLINIFNPE LVIIGGTLSL TGDYITQPIK
TAVRKYSLNL VNKDSAIMTS KLKDKAGIVG ACMLARSRMF ES
//
