ID A0A174WJG9_9CLOT Unreviewed; 231 AA.
AC A0A174WJG9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=adenosylhomocysteine nucleosidase {ECO:0000256|ARBA:ARBA00011974};
DE EC=3.2.2.9 {ECO:0000256|ARBA:ARBA00011974};
GN ORFNames=CP373A1_15180 {ECO:0000313|EMBL:OBY09673.1};
OS Clostridium paraputrificum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=29363 {ECO:0000313|EMBL:OBY09673.1, ECO:0000313|Proteomes:UP000092714};
RN [1] {ECO:0000313|EMBL:OBY09673.1, ECO:0000313|Proteomes:UP000092714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=373-A1 {ECO:0000313|EMBL:OBY09673.1,
RC ECO:0000313|Proteomes:UP000092714};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via salvage
CC pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-
CC thioadenosine (hydrolase route): step 1/2.
CC {ECO:0000256|ARBA:ARBA00004945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBY09673.1}.
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DR EMBL; MAPZ01000028; OBY09673.1; -; Genomic_DNA.
DR RefSeq; WP_027099098.1; NZ_UAWH01000019.1.
DR AlphaFoldDB; A0A174WJG9; -.
DR GeneID; 42776932; -.
DR eggNOG; COG0775; Bacteria.
DR OrthoDB; 9792278at2; -.
DR UniPathway; UPA00904; UER00871.
DR Proteomes; UP000092714; Unassembled WGS sequence.
DR GO; GO:0008782; F:adenosylhomocysteine nucleosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0008930; F:methylthioadenosine nucleosidase activity; IEA:InterPro.
DR GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; IEA:UniProtKB-UniPathway.
DR GO; GO:0009164; P:nucleoside catabolic process; IEA:InterPro.
DR CDD; cd09008; MTAN; 1.
DR Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR InterPro; IPR010049; MTA_SAH_Nsdase.
DR InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR NCBIfam; TIGR01704; MTA_SAH-Nsdase; 1.
DR PANTHER; PTHR46832; 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE; 1.
DR PANTHER; PTHR46832:SF1; 5'-METHYLTHIOADENOSINE_S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE; 1.
DR Pfam; PF01048; PNP_UDP_1; 1.
DR SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW Reference proteome {ECO:0000313|Proteomes:UP000092714}.
FT DOMAIN 2..227
FT /note="Nucleoside phosphorylase"
FT /evidence="ECO:0000259|Pfam:PF01048"
SQ SEQUENCE 231 AA; 24892 MW; 2F18EE5ED11DCEE1 CRC64;
MTLGIIAAMS EELEILLKDM QLDSSTTKAG MTFNKGKLWS NEVIAVVCGI GKVNAAVCTQ
ILVSEFNVDK VINVGVAGGI GKDIYPGDVV IATNLVEHDM DTTAFGDPHG QVPRMDTFDF
KCDSSLIESA NSACKKVGGF NTFTGRIVSG DVFVADVEKI KWLEKEFNAL SCEMEGASIA
HVCYLNNIPV VVIRSISDNA NNGAHMDFEK FTPIAVKNST SILKEMLLSM N
//
