ID A0A174ZJU2_CLOIN Unreviewed; 284 AA.
AC A0A174ZJU2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Patatin family protein {ECO:0000313|EMBL:MZH60468.1};
GN ORFNames=ADH65_14155 {ECO:0000313|EMBL:ASU19561.1}, GT649_10805
GN {ECO:0000313|EMBL:MZH60468.1}, I5Q87_09400
GN {ECO:0000313|EMBL:QQR28097.1};
OS Clostridium innocuum.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Coprobacillaceae; Thomasclavelia.
OX NCBI_TaxID=1522 {ECO:0000313|EMBL:MZH60468.1, ECO:0000313|Proteomes:UP000478871};
RN [1] {ECO:0000313|EMBL:ASU19561.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I46 {ECO:0000313|EMBL:ASU19561.1};
RX PubMed=29051233;
RA Garzetti D., Brugiroux S., Bunk B., Pukall R., McCoy K.D., Macpherson A.J.,
RA Stecher B.;
RT "High-Quality Whole-Genome Sequences of the Oligo-Mouse-Microbiota
RT Bacterial Community.";
RL Genome Announc. 5:e00758-17(2017).
RN [2] {ECO:0000313|Proteomes:UP000214713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=I46 {ECO:0000313|Proteomes:UP000214713};
RA Garzetti D.;
RT "High-quality whole genome sequences of the Oligo-Mouse-Microbiota.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:MZH60468.1, ECO:0000313|Proteomes:UP000478871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A13 {ECO:0000313|EMBL:MZH60468.1,
RC ECO:0000313|Proteomes:UP000478871};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
RN [4] {ECO:0000313|EMBL:QQR28097.1, ECO:0000313|Proteomes:UP000595712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=I46 {ECO:0000313|EMBL:QQR28097.1,
RC ECO:0000313|Proteomes:UP000595712};
RA Marbouty M., Lamy-Besnier Q., Debarbieux L., Koszul R.;
RT "Closed and high quality bacterial genomes of the OMM12 community.";
RL Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP022722; ASU19561.1; -; Genomic_DNA.
DR EMBL; WWTM01000019; MZH60468.1; -; Genomic_DNA.
DR EMBL; CP065320; QQR28097.1; -; Genomic_DNA.
DR RefSeq; WP_002606955.1; NZ_WWTY01000019.1.
DR GeneID; 61924163; -.
DR Proteomes; UP000214713; Chromosome.
DR Proteomes; UP000478871; Unassembled WGS sequence.
DR Proteomes; UP000595712; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07208; Pat_hypo_Ecoli_yjju_like; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR045943; DUF6363.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR037483; YjjU-like.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF25; PHOSPHOESTERASE-RELATED; 1.
DR Pfam; PF19890; DUF6363; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098}.
FT DOMAIN 6..172
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 284 AA; 32173 MW; 0A96595506A99BBD CRC64;
MSKLGLVLEG GGMRGIYTAG VLDFFMEQNL YTDGVIGVSA GACHACSYVS KQIGRAYRTN
TAYLKDKRYM SVSSLLKTGD FFGAKFVYED IPNTLDPYDF DAFNTSHTKL YAVASNLETG
KAEYLQCINM KRDVIYVRAS ASLPLLSRIV EVDGKKLLDG GATDSIPIHK FQEMGYTKNI
VVLTQCKEYR KGKNNLLPMI RRSYKKYPKF IKALETRHIA YNRTLDELAL MEKEGSVFLI
RPSSPVEISR LEKNEARLRE LYEQGYMDAK NSFEELKSFI ANEN
//
