ID A0A175AAJ4_CLOIN Unreviewed; 781 AA.
AC A0A175AAJ4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Anaerobic ribonucleoside triphosphate reductase {ECO:0000313|EMBL:MZH58836.1};
DE EC=1.17.4.2 {ECO:0000313|EMBL:MZH58836.1};
GN ORFNames=GT649_02215 {ECO:0000313|EMBL:MZH58836.1};
OS Clostridium innocuum.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Coprobacillaceae; Thomasclavelia.
OX NCBI_TaxID=1522 {ECO:0000313|EMBL:MZH58836.1, ECO:0000313|Proteomes:UP000478871};
RN [1] {ECO:0000313|EMBL:MZH58836.1, ECO:0000313|Proteomes:UP000478871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A13 {ECO:0000313|EMBL:MZH58836.1,
RC ECO:0000313|Proteomes:UP000478871};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MZH58836.1}.
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DR EMBL; WWTM01000003; MZH58836.1; -; Genomic_DNA.
DR RefSeq; WP_008816017.1; NZ_WWTY01000003.1.
DR AlphaFoldDB; A0A175AAJ4; -.
DR Proteomes; UP000478871; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd01675; RNR_III; 1.
DR Gene3D; 3.20.70.20; -; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR012833; NrdD.
DR NCBIfam; TIGR02487; NrdD; 1.
DR PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR Pfam; PF13597; NRDD; 1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00492}; Oxidoreductase {ECO:0000313|EMBL:MZH58836.1}.
FT DOMAIN 3..100
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
SQ SEQUENCE 781 AA; 87662 MW; 2ABE578959FF8E8D CRC64;
MITSIKKRDG REIHFSPEKI TRAIFLAASR VAQEEGSKAD YETAEILTEK VVNLLNNTYQ
GTTPTVENVQ DAVIKVLIET GHARTSEAYI LYRAERTRIR SMKTRLMKSI EEITFADSND
ADIKRENANI DGNTAMGTML QYGSAVSKEF CMSQLMNPQH AALHENGDIH IHDMDFMNMG
TLTCCQIDLE KLFNGGFSTG HGHLREPQDI TSYAALAAIA IQSNQNDQHG GQSIPAFDFY
LAKGVAKTFR KEYISNLNKA LELFINLDAD VREPFKAVEK ETGKTAAMIM DDSFLNSLNA
MLKETFGLGE EQIELINKFA YKEANVATRR KTYQAMEAFV HNLNTMHSRA GAQVPFSSIN
FGTDMTPEGR LISENLMLAQ EAGLGNGETP IFPILIFKVK EGINYNPEDP NYDLFKLAMR
VSAKRLFPNF SFMDAPFNKQ YYKEGHPETE TTYMGCRTRV MGNINGPEIA TGRGNNSFTS
INLPRLGIKH GVAVNGDFNE AAFFNELDEK MEIVIQQLLE RLEIQGRKKV KNFPFLMGQG
VWIGSENLSW EDTLEEIIKQ GTLTIGFIGL AECLKALIGE HHGESEEAQK LGLKIVGHMR
EMCDEATEKY GLNFSLIATP AEGLSGRFTR IDKKIYGIIP GVTDRDYYTN SFHVPVYYHI
TAFKKIQKEA PYHEFTNGGH ISYVEVDGDP TNNLEAFESI VRCMKDAGIG YGSINHPVDR
DPCCGYSGVI EGHVCPKCGR DEREEEYKFE KIRRITGYLV GTVDRFNDAK ASEERDRVKH
G
//
