ID A0A175VQ93_9PEZI Unreviewed; 504 AA.
AC A0A175VQ93;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Protein SSH4 {ECO:0000256|ARBA:ARBA00017626};
DE AltName: Full=Protein ssh4 {ECO:0000256|ARBA:ARBA00016528};
GN ORFNames=MMYC01_210416 {ECO:0000313|EMBL:KXX73677.1};
OS Madurella mycetomatis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariales incertae sedis; Madurella.
OX NCBI_TaxID=100816 {ECO:0000313|EMBL:KXX73677.1, ECO:0000313|Proteomes:UP000078237};
RN [1] {ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA van de Sande W.W.J.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KXX73677.1, ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA Van De Sande W.;
RT "Madurella mycetomatis genome sequencing.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Components of the endosome-vacuole trafficking pathway that
CC regulates nutrient transport. May be involved in processes which
CC determine whether plasma membrane proteins are degraded or routed to
CC the plasma membrane. {ECO:0000256|ARBA:ARBA00025244}.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004639}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004639}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004576}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004576}.
CC -!- SIMILARITY: Belongs to the SSH4 family.
CC {ECO:0000256|ARBA:ARBA00006990}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXX73677.1}.
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DR EMBL; LCTW02000437; KXX73677.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A175VQ93; -.
DR STRING; 100816.A0A175VQ93; -.
DR VEuPathDB; FungiDB:MMYC01_210416; -.
DR OrthoDB; 5479594at2759; -.
DR Proteomes; UP000078237; Unassembled WGS sequence.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR CDD; cd12910; SPRY_SSH4_like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035780; SPRY_Ssh4-like.
DR PANTHER; PTHR12864; RAN BINDING PROTEIN 9-RELATED; 1.
DR PANTHER; PTHR12864:SF54; SPRY DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000078237};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 78..274
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 313..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 54752 MW; EBDB5BAF4AE9B713 CRC64;
MAGYSPGPNG IVIGLLSSFG SAILILCIFL AFYFVRYTAS GRIFLDRIGR PGEYDDEQAF
ARDEAEALET MDDLQRTEYL RAKAFIAANP PESVQTDISL SQYLAIQEKG VSAWEFEPEL
EIANCFVEGR TEIEFFDSEC TVMSNLPVPK QNDVYYWEAK IFDKPENSLI SIGMATKPYP
LFRLPGFHKY SVAYLSNGTR RFNQPFAATP YGPHIVQGDV IGVGYRPRTG TIFFTRNGKK
LEDVVHGLKS QNFFPSVGAN GPCIVHVNFG QAGFVFIEAN VKKWGLAPMT GSLAPPPPYG
SEQGSILLEA GTKDGFTGSQ VRGHRHSHSV QVYSRQGPNT LDPGHTRSRS GNFRVLSPTS
PGPLRSPTDI SLAHLAPTDD TGEPSSSAAA LVSRGGEPPI SRRARCGRCQ QPPAPEYTSP
EHSDAETDSR RSSTDSENTP LIHLTRSRGG SLATARGRAS SSANNRSSPP RGPPSPPIPS
YQDAIQQGAG RDRSDSAMSA RSTR
//
