ID   A0A175VSB0_9PEZI        Unreviewed;      1248 AA.
AC   A0A175VSB0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=5-oxoprolinase {ECO:0000313|EMBL:KXX74406.1};
DE   Flags: Fragment;
GN   ORFNames=MMYC01_210287 {ECO:0000313|EMBL:KXX74406.1};
OS   Madurella mycetomatis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariales incertae sedis; Madurella.
OX   NCBI_TaxID=100816 {ECO:0000313|EMBL:KXX74406.1, ECO:0000313|Proteomes:UP000078237};
RN   [1] {ECO:0000313|Proteomes:UP000078237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA   van de Sande W.W.J.;
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KXX74406.1, ECO:0000313|Proteomes:UP000078237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA   Van De Sande W.;
RT   "Madurella mycetomatis genome sequencing.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXX74406.1}.
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DR   EMBL; LCTW02000355; KXX74406.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A175VSB0; -.
DR   STRING; 100816.A0A175VSB0; -.
DR   VEuPathDB; FungiDB:MMYC01_210287; -.
DR   OrthoDB; 674at2759; -.
DR   Proteomes; UP000078237; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000078237}.
FT   DOMAIN          1..99
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          118..423
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          653..1216
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
FT   REGION          1157..1183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1210..1248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KXX74406.1"
SQ   SEQUENCE   1248 AA;  135947 MW;  AD292565CBA5D6D9 CRC64;
     RVVEVAERVT LEDYAEDPER KATRVKARAG TEAAAREELV MGLSGEAVRI LLRPDREAVR
     AQLEEVYESG IRSIAVCLMH GYTFPDHERL IGEVASEIGF EHISLSHELM PMIKLVSRAT
     SVCADAYLTP AIKKYIAGFQ RGFEGGLGTK SVQPGAGKTG ARCEFMQSDG GLVDVDKFTG
     LKAILSGPAG GVVGYAITSY DEKTKIPVIG FDMGGTSTDM SRYGEGRYDH TFETTTAGVT
     IQSPQLDINT VAAGGGSMLF FRNGLFVVGP ESAGAHPGPA CYRKGGPATV TDANLFLGRL
     LPEFFPKIFG KNEDEGLDVE ASRRVLQELA DQIHNETGKK MDVDEVAYGF LTVANEAMTR
     PIRSITEAKG HDTSKHRLAT FGGAGGQHAV AIAESLGIKQ ILIHRYSSVL SAYGMALADV
     VDERQEPDST VWNEATEVVD QLKSKMESLK GKSRQALRDQ GFEDNEIVFE EYLNMRYRGT
     ESALMIIRPS EGERDWDFGA AFVKHHRYEF GFTLDGRDII VDDVRVRGIG KSFRYDEKSV
     DEQLKTIRRK EVLAQKKHSE AEVYFEGGRL KTPIYKLGDL SVGEVVKGPA MLADGTQTIV
     VTPNATALVL ETHVVIDIPE AEKDRYSEPP RFTLTTLTRP LRYSKASGER EVDPIMLSIF
     GHRFMAIAEQ MGRALQKTSV STNVKERLDF SCAIFDATGG LVANAPHLPV HLGSMSTCVR
     RQAEIWKGKL KKGDVIISNH PSYGGTHLPD VTLIMPAFNE AGDKILFYAA SRAHHADIGG
     ITAGSMPPHS RELHQEGAAV KSEKLVTEGK FNEERVIELF YKEPAKNPGC SGTRCLADNI
     NDLRAQVSAN QKGISLIEGL IAEYGEDTVQ FYMVAIQNNA ELQVRNLLRA VSKRFQGKDL
     SAEDFMDDGS PIRLRITIDA DKGEAVFDFA GTGPEVYGNI NAPEAISYSA IIYTLRCMIS
     EDIPLNQGCL KPITVRIPPG CFLSPSDGAA VVGGNVLTSQ RVTDVIFRAF EACAASQGDC
     NNLTFGFGGN LTGQAEVRGF GYYETIAGGS GAGPDWEGTD GVHVHMTNTR ITDSEVFERR
     YPVLLREFSI RRGSGGKGQH RGGDGVVRDI EFRIPVQVSI LSERRVYRPY GMAGGEDGQC
     GLNLWVRKVR KTSWESSLRK LQQSRSGGGG GGGDAEDDDE DEYEERRINL GAKNSAAMRA
     GDRIIVCTPG GGGWGKVGEA KVSKPKADPT QAWKKGSHAA REDLALQA
//