ID A0A175VX81_9PEZI Unreviewed; 885 AA.
AC A0A175VX81;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Probable endonuclease LCL3 {ECO:0000256|ARBA:ARBA00013404};
DE AltName: Full=Probable endonuclease lcl3 {ECO:0000256|ARBA:ARBA00014651};
GN ORFNames=MMYC01_207654 {ECO:0000313|EMBL:KXX75354.1};
OS Madurella mycetomatis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariales incertae sedis; Madurella.
OX NCBI_TaxID=100816 {ECO:0000313|EMBL:KXX75354.1, ECO:0000313|Proteomes:UP000078237};
RN [1] {ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA van de Sande W.W.J.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KXX75354.1, ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA Van De Sande W.;
RT "Madurella mycetomatis genome sequencing.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR017179}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXX75354.1}.
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DR EMBL; LCTW02000277; KXX75354.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A175VX81; -.
DR STRING; 100816.A0A175VX81; -.
DR VEuPathDB; FungiDB:MMYC01_207654; -.
DR OrthoDB; 375531at2759; -.
DR Proteomes; UP000078237; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016442; C:RISC complex; IEA:UniProtKB-UniRule.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:InterPro.
DR CDD; cd00175; SNc; 2.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 5.
DR InterPro; IPR016685; Silence_cplx_Nase-comp_TudorSN.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR12302; EBNA2 BINDING PROTEIN P100; 1.
DR PANTHER; PTHR12302:SF2; STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00565; SNase; 4.
DR Pfam; PF00567; TUDOR; 1.
DR PIRSF; PIRSF017179; RISC-Tudor-SN; 1.
DR SMART; SM00318; SNc; 5.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF50199; Staphylococcal nuclease; 5.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50830; TNASE_3; 4.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR017179};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000078237};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 3..142
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 165..307
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 316..453
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 482..615
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 697..757
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 609..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 97944 MW; 649EBA1E55235898 CRC64;
MAKSFLANVK SVLSGDTLIL TSPNNPAAER TLSLAYVSAP RLSKDGDEPF AFQSREFLRN
LTVGKPVKFS VSYTIPNSGR EYGTAVLQDG TELPEASVKA GWVKVREDAG RKEESEEVLD
KLDKLRGLET QAKDEGKGLH AGTGGVIEVQ NDLGGPKFMN EWKGKTVDGV IERVISGDRL
LVRLLLKEKK HWQVMTLIAG IRTPATERVN QSNGLTQPAE EYGNEARAFV EQRLLQRQVK
IKIVGASPQG QLVAAVLHPR GNIAEFLLQE GLARCNDFHS TMLGNDMAAL RAAEKQAQAA
RRRLHKAFVA KATDTKESDA TVVKIIGADT IIVRNKAGAE KRISLSSVRG PRAGEASEAP
FRDEAKEFLR KKLIGKHIRI SVDGTKAATE EFEARDVATV IQGGKNIGLQ LVQEGYCSVI
RHRKDDTDRA PNYDELLAAQ ETAKEEKKGM WSGKPPKVKQ YVDMSESVQK AKIQLSTLSR
QRKVPGIVDF CKSGSRFTIL IPREGAKITL VLAGVRAPRA GRTPQEKGEP FGQEALDLAN
RRCNQRDCEI DVHDIDKVGG FIGDLYVNRE SFAKILVEEG LASVHQYSAE KSGNATELLA
AQKRAKEARK GMWHDWDPSQ DAEEESEAAP AESSVDASTT IEKKPEDYRD IMVTNVDSNG
KIKVQEIGKG TDALEALMEQ FRQFHLNPTN SATIKDAPKA GDYVAAQFSE DGEWYRARIR
SNDRAAKVAE VVYIDYGNSE KQPWSKLRPL NQPQFAVQKL KPQAVDTQLS FVQLPASPDY
LSDAINYLYE LTEGKRLVGS FDYVDAKEGL SYVTIFDPKA EGSNKVTESI NRQMVLNGHA
LVARKLKAWE RSKVFEPVIK NLREAEAEAK EGRRGIWEYG DITED
//
