ID A0A175VYT8_9PEZI Unreviewed; 943 AA.
AC A0A175VYT8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cullin-4B {ECO:0000313|EMBL:KXX76455.1};
GN ORFNames=MMYC01_206682 {ECO:0000313|EMBL:KXX76455.1};
OS Madurella mycetomatis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariales incertae sedis; Madurella.
OX NCBI_TaxID=100816 {ECO:0000313|EMBL:KXX76455.1, ECO:0000313|Proteomes:UP000078237};
RN [1] {ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA van de Sande W.W.J.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KXX76455.1, ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA Van De Sande W.;
RT "Madurella mycetomatis genome sequencing.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXX76455.1}.
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DR EMBL; LCTW02000210; KXX76455.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A175VYT8; -.
DR STRING; 100816.A0A175VYT8; -.
DR VEuPathDB; FungiDB:MMYC01_206682; -.
DR OrthoDB; 5474206at2759; -.
DR Proteomes; UP000078237; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000078237}.
FT DOMAIN 553..817
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 1..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 943 AA; 104218 MW; 4963F3978450B7E8 CRC64;
MPPPNPTAFS SASSPTSVPR RRQRVDSSSD VNPDPSNGPR QSRPDLKRPR SDLYAPPATS
TASATTTATT MSAKVQGKRP EVIDLTRQVT PPMQHPHHHP HQQHLKHSSH TPSLFSSRSS
TPLQPHVGSR KLVVKNLRPP TAPRPTAPAA VDSYYAGVRA DLDAALSAIF AGRPTPQPME
RLYRGVEDIC RKGEAAELTE RLRARCEAWL NDGQGEMLGG LWARYAATVG AAAVGGSSSG
GGGGSSSDGG VGEGAGDALL RGVVERWKRW GDVLFVVRGL YSYLDRAYLL LQGGGGGGKQ
GVNEMGIELF RKAVFGSRRD PNVAPQGLRV LEAVCRMVDY VRRGDERQDE ALLKEAVAML
RLCGVYGRSF EPMFLVKSHR YLEAFAAEMS AMYGLKGYIS AVGTLLQKES DRCDGYNFES
TTKKQLLEDA HHVLIEQYSD KLLDSGSVGR LLEAGDVESV KALYELLKLS GLQKRLKGPW
ERYVRDTGAA IVSDTQRGDD MVIRLLELRR SLDIMIRDAF AKDEVFVYGL RESFGHFIND
KKSSSSWNTG TSKVGEMIAK YIDMLLRGGL KTLPKSLLSD SKDRADAEMS GVASTGDEDA
ELDRQLDYGL ELFRFIEGKD VFEAFYKKDL ARRLLLGRSA SQDAERSMLA KLKSECGSSF
THNLEQMFKD QELAKDEMTS YKEWLAGTGR SNGGVDLSVS ILSAAAWPTF PDVRVLLPKE
VLEQITIFDK YYKNKHTGRR LTWKHNMAHC VVKAQFNRGP KELLVSALQA AVLMLFNDVE
DDGSKKTSTS GVLSYEQISQ ATGLQGGELD RTLQSLACGK ARVLTKHPKG RDVSPTDTFT
VNKAFTDPKF RVKINQIQLK ETKEENRETH ARVAADRQFE TQAAIVRIMK SRKKMGHVQL
VAEVINQTRS RGAVDPADIK ANIEKLIEKD YLEREGGYYI YLA
//
