ID   A0A175W3M5_9PEZI        Unreviewed;       785 AA.
AC   A0A175W3M5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Griffithsin {ECO:0000313|EMBL:KXX78263.1};
GN   ORFNames=MMYC01_204007 {ECO:0000313|EMBL:KXX78263.1};
OS   Madurella mycetomatis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariales incertae sedis; Madurella.
OX   NCBI_TaxID=100816 {ECO:0000313|EMBL:KXX78263.1, ECO:0000313|Proteomes:UP000078237};
RN   [1] {ECO:0000313|Proteomes:UP000078237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA   van de Sande W.W.J.;
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KXX78263.1, ECO:0000313|Proteomes:UP000078237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA   Van De Sande W.;
RT   "Madurella mycetomatis genome sequencing.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXX78263.1}.
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DR   EMBL; LCTW02000127; KXX78263.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A175W3M5; -.
DR   VEuPathDB; FungiDB:MMYC01_204007; -.
DR   OrthoDB; 3022046at2759; -.
DR   Proteomes; UP000078237; Unassembled WGS sequence.
DR   Gene3D; 2.100.10.30; Jacalin-like lectin domain; 1.
DR   InterPro; IPR001229; Jacalin-like_lectin_dom.
DR   InterPro; IPR036404; Jacalin-like_lectin_dom_sf.
DR   InterPro; IPR021917; Unchr_Zn-peptidase-like.
DR   PANTHER; PTHR21054:SF2; MIP04191P; 1.
DR   PANTHER; PTHR21054; ZINC METALLOPROTEINASE-RELATED; 1.
DR   Pfam; PF01419; Jacalin; 1.
DR   Pfam; PF12044; Metallopep; 1.
DR   SMART; SM00915; Jacalin; 1.
DR   SUPFAM; SSF51101; Mannose-binding lectins; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR   PROSITE; PS51752; JACALIN_LECTIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000078237}.
FT   DOMAIN          636..785
FT                   /note="Jacalin-type lectin"
FT                   /evidence="ECO:0000259|PROSITE:PS51752"
FT   REGION          1..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..58
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   785 AA;  85368 MW;  84EE2B3C4DF88CFE CRC64;
     MAPLSFSFKE FRRRSKASFR TQRSTDSTSS EASNVTSPSS GSLTPPSISQ QSDPALNLQL
     KDTPPAAPRP RPQPHPHPNV ASNRYSVSGM AGLGSPVPGG KGPALPVSQY SPRITNVPDS
     SWVYQKVLLV YGVIGEPSHH SLDGTLTVSR LDDSFPSISW PVCNSRFKAL VYLMPGANRL
     RFDFASPKLA NSGSSNPIHA SYLTVHMIPP VGAPPLQLAI LLAKDSPGTF DAVPARIERE
     GNGLDTAVRK FRMAAYLWQA FTAEQMWRNK LGRRAFRFEE EWTTGAANQR DREHGTLRSE
     ARVHIIRTDK TIAELQDLNL AQQNKNATDA GGLYRIAADA VRNHFKPLPG QKLYVSVLLL
     DAHWDASSKT ILGHAALGGQ SGDIHLGIFG SHCLQSYPAS FEEVVPAFSD CTPTDTNRVA
     NDCNDAGSSW EAANIGIGAH LHETGHLLGL PHQESGIMAR GYVTLNRTFL SREAYSTRTR
     SRGGPVSQDD ECTWHRLDCL RFRSHPCFRL PNDPVLNPDD SVQAWPMEGG NLTVTAATGV
     AYVEIYAGSA DGGGGGDDVC RAWIEYPADN GNGMQRMVAL TEQDLRSRLP DETKRKGRLR
     ISVKSHGGGS LDIDDFAKLC AKETACLKLP SAVPGLPKTA FRGKTVGLSQ MEGSAPQELV
     FSSALRQDRV LSRIVFYHGA AVDGLEFVYD DDSRQLFGKK GGKEGGDSFE MDIRRGEYIT
     GFFVRSGFWI DAIQVLTSLG RRSPLFGNPH GGDTHTLIPP RGYNICGVTG SCGPWLDGFS
     VIITR
//