ID A0A175W430_9PEZI Unreviewed; 1783 AA.
AC A0A175W430;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cytokinesis protein sepA {ECO:0000313|EMBL:KXX78423.1};
GN ORFNames=MMYC01_203485 {ECO:0000313|EMBL:KXX78423.1};
OS Madurella mycetomatis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariales incertae sedis; Madurella.
OX NCBI_TaxID=100816 {ECO:0000313|EMBL:KXX78423.1, ECO:0000313|Proteomes:UP000078237};
RN [1] {ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA van de Sande W.W.J.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KXX78423.1, ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA Van De Sande W.;
RT "Madurella mycetomatis genome sequencing.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the formin homology family. BNI1 subfamily.
CC {ECO:0000256|ARBA:ARBA00037935}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXX78423.1}.
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DR EMBL; LCTW02000120; KXX78423.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A175W430; -.
DR STRING; 100816.A0A175W430; -.
DR VEuPathDB; FungiDB:MMYC01_203485; -.
DR OrthoDB; 1118745at2759; -.
DR Proteomes; UP000078237; Unassembled WGS sequence.
DR GO; GO:0015629; C:actin cytoskeleton; IEA:UniProt.
DR GO; GO:0005938; C:cell cortex; IEA:UniProt.
DR GO; GO:0032153; C:cell division site; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProt.
DR Gene3D; 6.10.30.50; -; 1.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.10.238.150; Formin, FH3 diaphanous domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR47102; PROTEIN BNI1; 1.
DR PANTHER; PTHR47102:SF2; PROTEIN BNI1; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000078237}.
FT DOMAIN 263..689
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 1125..1546
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 1559..1591
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 879..916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 971..1029
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1531..1761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1415..1442
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 978..998
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1273..1287
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1692..1727
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1783 AA; 198700 MW; D3210FCC01B69742 CRC64;
MSSYDKSRAS STGKASSFFH RSKNKADKKN TGDDGRHLAA NNDNTSGSVS SRTSRHQRES
SVISIDRPSS AESGINMMAG VMTTIPYESV SADHRSPVPV DYIPQGDQMP VRREPLPHQL
NKATSDFHQY PSFEHVSTPY LSGQRPPPGA SNITMASTGR QAQYQQWGPP RDSSLAGSHS
SRYNSYMTSG GRSSADNLSV LSGNGGPFFE QRAAHRSSRL AQAAAPGASS PTSSYLSPHS
PRDGHRLTKF PSGYQTSEGF QLPKPEDDGV IEQMFLALMQ KRGWHNLPDQ AKRQMVAYPA
QKKWTLIYQD ALTEWQGEQK RRNTAKIGQY SNVDLSQLPD EEGSPEWYVR KVMENSLDTK
GFGSLEVNLR TQQIGWVKRF IECQGQVALT NVLMKLNRRG AMGQAQDAGK GDKNLDREYD
IVKCLKALMN NKFGADDALA HQQVLVALAT CLISPRLSTR KLVSEVLTFL CHWSDGKGHV
KVIEAMDVAK NQQGENGRFD AWMRLVEVTV DGRGKMGSLV GASDEVRSGG IGMENLLMEY
AVATLILINM LIDAPEKDLQ LRVHIRAQFT ACGIKRMLTK MESFQYELID KQIERFRTNE
AIDYEDMLER ENSSIKDSVD GEVRDLNDPV QIVDAIQQRL KGSKTQDYFI SALQHLLLIR
DNDGEERLRM FQLVDSMLSY VAMDRRLPDM DLKQSLNFTV QSLLDKLHTD SEARQAFDEA
TESRQIAEAA MAERDELREK LALGADGLVA KLQKQIDEQA RFIEAQRRLT EGLKSELESM
QTVRAKEAQR YELETRELYL MLRDAQDVAA SNAAKGNKLG DEDPARMQGI LDREKLMERL
QMQLERQKTV YKLEGRVWGE AIGPSDRLRA LREEMDGFGD SGLGAGTPPR DFTNSMLGSV
QRSTRIPRKP VGARAEHADD ILEEEVEDTV EDEEGVVYEK PRLVEIKRPV MDPKQAAGMF
NELQDKVKRF DASDSEGEGV TTGPSHPSLE SQFPVTPSDT EPPKIKITDT YPPGPASTAS
GGPPPPPRRL LHHYRVTYPV RRPLWLPRSP AKSQVVLLHL LHHPLPLRPA ISRVLRLRLR
LLRLLRPANF PGMPPPPPPP MPGPGAMSGH FLSRQQDFTQ APSLGLSIAR PKKKLKALHW
EKVDSPVATH WAAHTPSAEE REEKYLELSR KGILDEVEKL FMAKEIKQIG QGTAKKDDKK
QIISNDLRKA FEIALAKYSQ YSVEKVVQMI IHCDKEVLDN PVVMEFLQKE EICNIPDNTA
KLMAPYSKDW TGPEANKENR EQDPSELTRQ DQIYLQTAFE LHHYWKSRMR ALSLTRSFEA
DYDEITEKMR QVVSVSESLR DSVSLMNILG LILDIGNYMN DANKQARGFK LSSLARLGMV
KDDKNQSTLA DLVERIVRHQ YPEWGNFADD IGGVLTAQKI NIEQLQADAK KYIDNVRNVQ
MSLDSGNLAD PKKFHPQDRV AQVVQRCMKD ARRKAEQMQV YLEEMVRTYN DIMAFYGEDP
TDDNARRDFF SKLALFITDW KKSHTKNLEL EEQRKKNEAS MKRKNALKTA QAAEGMPASP
TSTGAMDSLL EKLRAAAPQA RDQRDRRRRA RLKDRHQVRI ASGQKMPDLD QEASEGQAQG
ETGGVPPGQG PGSEVTDEDG KASKTDLLSP TAAKDADASA AAAAGGAGGE EDDVAQRAAL
LLQGMRSGAD GADDPADAEK RENLRRSRRQ TADEERRMRR RRREMAQSSA SNGDVSGKED
GPGGGGSADV PPTPSAEEFA AAVAAAGVEV ASPTAGGHVN GTS
//
