ID A0A175WBX1_9PEZI Unreviewed; 854 AA.
AC A0A175WBX1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744, ECO:0000256|RuleBase:RU361161};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744, ECO:0000256|RuleBase:RU361161};
GN ORFNames=MMYC01_203815 {ECO:0000313|EMBL:KXX80730.1};
OS Madurella mycetomatis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariales incertae sedis; Madurella.
OX NCBI_TaxID=100816 {ECO:0000313|EMBL:KXX80730.1, ECO:0000313|Proteomes:UP000078237};
RN [1] {ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA van de Sande W.W.J.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KXX80730.1, ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA Van De Sande W.;
RT "Madurella mycetomatis genome sequencing.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448,
CC ECO:0000256|RuleBase:RU361161};
CC -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC {ECO:0000256|ARBA:ARBA00004987, ECO:0000256|RuleBase:RU361161}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXX80730.1}.
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DR EMBL; LCTW02000052; KXX80730.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A175WBX1; -.
DR STRING; 100816.A0A175WBX1; -.
DR VEuPathDB; FungiDB:MMYC01_203815; -.
DR OrthoDB; 5486783at2759; -.
DR UniPathway; UPA00696; -.
DR Proteomes; UP000078237; Unassembled WGS sequence.
DR GO; GO:0008422; F:beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102483; F:scopolin beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF12; BETA-GLUCOSIDASE A-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|RuleBase:RU361161};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000078237};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..854
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008043879"
FT DOMAIN 766..834
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
SQ SEQUENCE 854 AA; 91868 MW; E69EF7372D2681E0 CRC64;
MANLVLALLL FLSALTSAAT DTPFLGYPSP WATNITDPTW AAAYAQAIAF VANLTLTEKV
NLTTGTGWEA DRCIGATGGI PRLGFRPFCL MDGPLGVRYT DHNSAFPAGV NTAATFSRRL
MRLRGEAMGA EFRGKGIDVM LGPVAGALGR VPQGGRNWEG FSPDPYLTGV AMAETIQGIQ
SRGVVACAKH YILNEQEHFR GSIDVRIDDR TMHELYLWPF ADAVRAGVGS VMCSYNKING
TYACENEWTT NYLLKNELGF QGFVLSDWGA QHNTLGSALG GLDMAMPGDG GPPPYRAWWG
GALTEAVLRG DVPQWRLDDM AVRIMAAYFR VHTGNYTSRP DINFSAWTNS TVGPLYPAAN
QSYTVVNEFV DVQSDHASLI REIGAKSVVL LKNAYDLLPL RQPGPPIIAV IGDDAQDHPL
GPNACPERGC LNGTLAMGYG SGTANFPYLV SPLTALTEQA RADNTTLLYA PSNWDLDAAI
TTARNASIAI VFAAATSGEN FITVDGNAGD RNNLTLWANG DALIKAVASI NPNTIVVLHT
PGPVILDYAE EHPNISAILW AGLPGQESGN ALVDVLYGKV NPQGRSPFTW GDSVEEYGAQ
LMFEAENPRA PVQSFDEGVF IDYRKFSTFG GKLTYPFGFG LSYTKFRYSG LSVVRKEEVE
GRFEPAEGLT GPAPTFGVVE AELGVHTAPE GFTRISPYVY PWLNNSESLV TGNSTGASEF
PAAARNGSAQ PVLPASGAPG GNPGLYEVLY TITASIENVG EVAGTEIPQL YVQLGGEENP
FGVLRGFDEV ELEPGETKNV TFELTRRDVS NWNTSTQNWE ITDREKVVFV GSSVRDIRLN
ASLPAPVGMA WRHG
//
