ID A0A175WJK0_9PEZI Unreviewed; 240 AA.
AC A0A175WJK0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 7 {ECO:0000256|ARBA:ARBA00020631, ECO:0000256|RuleBase:RU364060};
GN ORFNames=MMYC01_200473 {ECO:0000313|EMBL:KXX83034.1};
OS Madurella mycetomatis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariales incertae sedis; Madurella.
OX NCBI_TaxID=100816 {ECO:0000313|EMBL:KXX83034.1, ECO:0000313|Proteomes:UP000078237};
RN [1] {ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA van de Sande W.W.J.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KXX83034.1, ECO:0000313|Proteomes:UP000078237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mm55 {ECO:0000313|Proteomes:UP000078237};
RA Van De Sande W.;
RT "Madurella mycetomatis genome sequencing.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC the regulated transcription of nearly all RNA polymerase II-dependent
CC genes. Mediator functions as a bridge to convey information from gene-
CC specific regulatory proteins to the basal RNA polymerase II
CC transcription machinery. Mediator is recruited to promoters by direct
CC interactions with regulatory proteins and serves as a scaffold for the
CC assembly of a functional preinitiation complex with RNA polymerase II
CC and the general transcription factors. {ECO:0000256|ARBA:ARBA00025687}.
CC -!- SUBUNIT: Component of the Mediator complex.
CC {ECO:0000256|ARBA:ARBA00011837, ECO:0000256|RuleBase:RU364060}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364060}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 7 family.
CC {ECO:0000256|ARBA:ARBA00009994, ECO:0000256|RuleBase:RU364060}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXX83034.1}.
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DR EMBL; LCTW02000004; KXX83034.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A175WJK0; -.
DR STRING; 100816.A0A175WJK0; -.
DR VEuPathDB; FungiDB:MMYC01_200473; -.
DR OrthoDB; 11599at2759; -.
DR Proteomes; UP000078237; Unassembled WGS sequence.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.140.1520; -; 1.
DR Gene3D; 6.10.140.200; -; 1.
DR InterPro; IPR037212; Med7/Med21-like.
DR InterPro; IPR009244; Mediatior_Med7.
DR InterPro; IPR044888; Mediatior_Med7_sf.
DR PANTHER; PTHR21428; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7; 1.
DR PANTHER; PTHR21428:SF11; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7; 1.
DR Pfam; PF05983; Med7; 1.
DR SUPFAM; SSF140718; Mediator hinge subcomplex-like; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159, ECO:0000256|RuleBase:RU364060};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364060};
KW Reference proteome {ECO:0000313|Proteomes:UP000078237};
KW Transcription {ECO:0000256|RuleBase:RU364060};
KW Transcription regulation {ECO:0000256|RuleBase:RU364060}.
SQ SEQUENCE 240 AA; 27417 MW; D286EB39976EA4D7 CRC64;
MDNHDDDTSR VTSLWPDPVP FWKDFTPENL ARYENLKQDY ARQQELNADA VIRVPDIPED
LINLQPPPEP SDGKWRLFGE SEKACLEDAG IQRLAPATET DKDSKHLDRG FELKKLAKSI
LLNYLELVGI MSHNPAHAVE KIQDLKTLLL NFHHILNEYR PHQAREQLIQ LMQDQLDSKR
AETAGIRSVV DKAKRMIEGL ASIEVPRLDA AVEKEPLDAD GDKPRRYEIT VWAQLDAEVA
//
