ID A0A175YJC0_DAUCS Unreviewed; 604 AA.
AC A0A175YJC0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=EGF-like calcium-binding domain-containing protein {ECO:0000259|SMART:SM00179};
GN ORFNames=DCAR_028923 {ECO:0000313|EMBL:KZM83655.1};
OS Daucus carota subsp. sativus (Carrot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=79200 {ECO:0000313|EMBL:KZM83655.1};
RN [1] {ECO:0000313|EMBL:KZM83655.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaf {ECO:0000313|EMBL:KZM83655.1};
RX PubMed=27158781; DOI=10.1038/ng.3565;
RA Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D., Ashrafi H.,
RA Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT "A high-quality carrot genome assembly provides new insights into
RT carotenoid accumulation and asterid genome evolution.";
RL Nat. Genet. 48:657-666(2016).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00029430}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00029430}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004614}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004614}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}. Prevacuolar compartment membrane
CC {ECO:0000256|ARBA:ARBA00043947}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00043947}.
CC -!- SIMILARITY: Belongs to the VSR (BP-80) family.
CC {ECO:0000256|ARBA:ARBA00007038}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZM83655.1}.
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DR EMBL; LNRQ01000008; KZM83655.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A175YJC0; -.
DR STRING; 79200.A0A175YJC0; -.
DR EnsemblPlants; KZM83655; KZM83655; DCAR_028923.
DR Gramene; KZM83655; KZM83655; DCAR_028923.
DR OMA; EVYECAI; -.
DR Proteomes; UP000077755; Chromosome 8.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd02125; PA_VSR; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR PANTHER; PTHR22702; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22702:SF1; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02225; PA; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000077755};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 544..567
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 494..536
FT /note="EGF-like calcium-binding"
FT /evidence="ECO:0000259|SMART:SM00179"
SQ SEQUENCE 604 AA; 67206 MW; C6FF4E441B24974A CRC64;
MGRFVVEKNS LKVTSPDKLK DTYECAIGNF GIPQYGGTLV GAVIYPKSNQ KACKTFDDDA
SFKSKPGSLP IFLLADRGDC YFTLKAWNAQ NAGAAAILVA DDRVEPLITM DTPEEEDARA
DYLQNITVPS ALISKSLGDS IKKALSNGDM VNINLDWREA LPHPDERVEY EFWTNSNDEC
GPKCESQIDF VKSFKGVAQI LERKGYTQFT PHYITWYCPE AFTLSKQCKS QCINHGRYCA
PDPDQDFNKG YDGKDVVVQN LRQACLYKVA NESGKPWFWW DYVTDFAIRC PMKDKKYTKE
CADQVIQSLG VDLKQIDKCI GDPTADVDNT ILKTEQEAQI GKGSRGDVTI LPTLVINNRQ
YRGKLDKGAV LKAICSGFEE TTEPDVCLSE EIETNECLEN NGGCWQDKAA NITACKDTFR
GRVCQCPIVQ GVKFSGDGYT HCEASGSLRC EINNGGCWRK TQNGRTYSAC IDDHTKGCKC
PPGFKGDGVN NCEDIDECKA KTACQCPECK CKNTWGSYDC SCSGNLLYMR EHDTCISKDV
SAEVSWGFVW VIILGLAAAG VGGYAVYKYR IRRYMDSEIR AIMAQYMPLD NQPEDPVHHS
HGNV
//
