ID A0A176J1N4_9BACI Unreviewed; 679 AA.
AC A0A176J1N4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:KZZ82834.1};
GN ORFNames=AS29_018695 {ECO:0000313|EMBL:KZZ82834.1};
OS Bacillus sp. SJS.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1423321 {ECO:0000313|EMBL:KZZ82834.1, ECO:0000313|Proteomes:UP000028527};
RN [1] {ECO:0000313|EMBL:KZZ82834.1, ECO:0000313|Proteomes:UP000028527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJS {ECO:0000313|EMBL:KZZ82834.1,
RC ECO:0000313|Proteomes:UP000028527};
RA Newman J.D., Stropko S.J., Pipes S.E.;
RT "Bacillus sp. SJS genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZZ82834.1}.
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DR EMBL; JAQV02000031; KZZ82834.1; -; Genomic_DNA.
DR RefSeq; WP_035411890.1; NZ_JAQV02000031.1.
DR AlphaFoldDB; A0A176J1N4; -.
DR STRING; 1423321.AS29_018695; -.
DR eggNOG; COG1298; Bacteria.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000028527; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000028527};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 93..119
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 188..210
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 287..306
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 679 AA; 73621 MW; CD8A7DA258012385 CRC64;
MSTRDLSVLF SVVLIVAMLI IPFPTWLLSL LIICNISLAL LVLLTTMNMR EPLEFSIFPS
LLLLLTLFRL GLNVSTTRAI LSNGEGGKVV ETFGTFVVGG NVLVGFVVFI ILVIIQFVVI
TKGSERVSEV AARFTLDAMP GKQMSIDADL NAGMISEQEA RVRREKVGNE ADFYGAMDGA
SKFVKGDAIA GIIIVIINLI FGMIVGVVQQ GMPFAEAASH FTMLSVGDGI VSQIPALLIS
TATGIVVTRA ASEGNLGGDI SKQLFAYPQM MYVAAGSMMM LGLFTPIGLL VTAPIGGALA
FGAYVMQQSQ KKLKEVPESE LEMQPDPEEM KSPESIVQLL SMDPIEFEFG YGLIPLADSS
QGGDLLDRIV MIRRQLAIEL GIVIPVVRIR DNIQLQPNEY RLKIKGSEAA RGDLLLEHYL
AMAPGADEDA IEGIDTIEPS FGLPAKWISE AMKDQAELYG YTVVDPPSVV STHITETIKK
HASELLGRQE TKQLIDHLKE AYPILVDEVT PSPLSIGDIQ KVLSNLLKEN VSIRNLPVIF
ETLADYGKMT SDSDILTEYA RQALAKQITQ AFSGDGQVLK VVTLSGRVEK LVAEGVQQTE
HGNYLSLDPS VSQAIIESVA KEIESLSLQG NSPVLLCSPA VRMYVKQLLE RYFPAVPVLS
YNELESNVEV QSVGVVNVA
//
