ID   A0A176J2E2_9BACI        Unreviewed;       321 AA.
AC   A0A176J2E2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Dimethylhistidine N-methyltransferase {ECO:0000313|EMBL:KZZ83083.1};
GN   ORFNames=AS29_020060 {ECO:0000313|EMBL:KZZ83083.1};
OS   Bacillus sp. SJS.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1423321 {ECO:0000313|EMBL:KZZ83083.1, ECO:0000313|Proteomes:UP000028527};
RN   [1] {ECO:0000313|EMBL:KZZ83083.1, ECO:0000313|Proteomes:UP000028527}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SJS {ECO:0000313|EMBL:KZZ83083.1,
RC   ECO:0000313|Proteomes:UP000028527};
RA   Newman J.D., Stropko S.J., Pipes S.E.;
RT   "Bacillus sp. SJS genome.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZZ83083.1}.
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DR   EMBL; JAQV02000031; KZZ83083.1; -; Genomic_DNA.
DR   RefSeq; WP_035413263.1; NZ_JAQV02000031.1.
DR   AlphaFoldDB; A0A176J2E2; -.
DR   STRING; 1423321.AS29_020060; -.
DR   eggNOG; COG4301; Bacteria.
DR   OrthoDB; 5289726at2; -.
DR   Proteomes; UP000028527; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR035094; EgtD.
DR   InterPro; IPR019257; MeTrfase_dom.
DR   InterPro; IPR017804; MeTrfase_EgtD-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   NCBIfam; TIGR03438; egtD_ergothio; 1.
DR   PANTHER; PTHR43397; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR   PANTHER; PTHR43397:SF1; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR   Pfam; PF10017; Methyltransf_33; 1.
DR   PIRSF; PIRSF018005; UCP018005; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:KZZ83083.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028527};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KZZ83083.1}.
FT   DOMAIN          22..319
FT                   /note="Histidine-specific methyltransferase SAM-dependent"
FT                   /evidence="ECO:0000259|Pfam:PF10017"
SQ   SEQUENCE   321 AA;  36481 MW;  A915E184B183756D CRC64;
     MTTLKQAIQF TDNGVEYSSF LTEVLDGLKR VPKTLPAKFL YDERGSELFE EITNLAEYYP
     TRTEIDILES VKNEIALLIG PEAALIEFGS GSSRKIQILL QSLKDLSVYV PIDISKEFLY
     ASSLKLAHDY PTLHIHAVSG DYTAPMTLPD LNCRKKAAFF PGSTIGNFEP REAGAFLDTV
     AAMLEKGDGF LVGVDLKKES HILHSAYNDA RGITAEFNLN LLRRMNRELG ADFALDAYRH
     HAFYNEEKGR IEMHIISQKD QKVTIQSEEI VIQRGETIHT ENSYKYEVEE FHNLASKSGF
     AARKFWTDQN RLFSLHYLEL R
//