ID A0A176L2D2_9ACTN Unreviewed; 485 AA.
AC A0A176L2D2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:OAA98657.1};
GN ORFNames=A6P39_21885 {ECO:0000313|EMBL:OAA98657.1};
OS Streptomyces sp. FXJ1.172.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=710705 {ECO:0000313|EMBL:OAA98657.1};
RN [1] {ECO:0000313|EMBL:OAA98657.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FXJ1.172 {ECO:0000313|EMBL:OAA98657.1};
RA Liu M., Liu N., Shang F., Huang Y.;
RT "Activation and identification of NC-1, a novel cryptic cyclodepsipeptide
RT from red soil-derived Streptomyces sp. FXJ1.172.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA98657.1}.
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DR EMBL; LWRP01000105; OAA98657.1; -; Genomic_DNA.
DR RefSeq; WP_067048702.1; NZ_CP119133.1.
DR AlphaFoldDB; A0A176L2D2; -.
DR STRING; 710705.A6P39_21885; -.
DR OrthoDB; 9766847at2; -.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 154..479
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 485 AA; 50944 MW; 09BB1C92D0860C7C CRC64;
MNKTIRRASV FALLLVLTLL VRATWVQFYD GKALADDNDN RRNAIQTYSQ PLGNIIVAGN
AITGSARTKG SDLAYKRTYT DGRLYAAVTG YASQAYAPTQ LEGIYQDLLN GTDTRLKNVL
DTLTGKRADP GNVLTTIDPA VQKAAYQALG GKKGAAVAID PKTGKILAVV STPSYDPSSL
TDANTAGTAW KQLGADKDKP LTNRALRQPL PPGSTFKLVV AAAALEDGLY KNVDEHTDSP
NPYTLPGTVR PLANENASAP CENAPIRVAL QYSCNNVFGK MAVDLGQDKV RAMAEKFGFN
DDQLDVPVRA YASVYPSHMD KAQTGLSGIG QFDVTATPLQ MAMVSAAIAN GGKLVSPHMV
SQLTDSGGDV LHDYDSDAGT RQVVSSATAG QLQSAMETVV KDGTGTNALI DGVTVGGKTG
TAQHGENNSK TPYAWFTSFG KSDSSGKEVA VAVMVEQSDA ARSEVSGNGL AAPVAKAMMR
AALKS
//
