ID A0A176L2S0_9ACTN Unreviewed; 433 AA.
AC A0A176L2S0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=PTS lactose transporter subunit IIC {ECO:0000313|EMBL:OAA98852.1};
GN ORFNames=A6P39_21200 {ECO:0000313|EMBL:OAA98852.1};
OS Streptomyces sp. FXJ1.172.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=710705 {ECO:0000313|EMBL:OAA98852.1};
RN [1] {ECO:0000313|EMBL:OAA98852.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FXJ1.172 {ECO:0000313|EMBL:OAA98852.1};
RA Liu M., Liu N., Shang F., Huang Y.;
RT "Activation and identification of NC-1, a novel cryptic cyclodepsipeptide
RT from red soil-derived Streptomyces sp. FXJ1.172.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA98852.1}.
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DR EMBL; LWRP01000104; OAA98852.1; -; Genomic_DNA.
DR RefSeq; WP_067048248.1; NZ_CP119133.1.
DR AlphaFoldDB; A0A176L2S0; -.
DR STRING; 710705.A6P39_21200; -.
DR OrthoDB; 9797715at2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR PANTHER; PTHR30009; CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT; 1.
DR PANTHER; PTHR30009:SF4; PTS SYSTEM N-ACETYLGLUCOSAMINE-SPECIFIC EIICBA COMPONENT; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 65..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..423
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
SQ SEQUENCE 433 AA; 46159 MW; CF1E7D272BC3478F CRC64;
MSTQAEVSPA RARWNRAFQG LQKMGRSLQL PIAVLPAAGI LNRLGQPDVF GDAGLHWTNV
SKVMVGAGGA LLDGSLGLPL LFCVGVAIGM AKKADGSTAL AAVAGFLVYY GVLHQFPQSC
PGGSKAVPQV GCQVSGGAGV GAVTPFTFQN PGVFGGIVMG LLAAFFWARF HRTRLVDWLG
FFNGRRLVPI IMAFVAIVFA ALCLWVWPPI GGGLESFSRW LRDAGAWGAG VFGVANRALL
VVGLHQFLNV PIWFQFGSYT KPDGTVVHGD INMFLAGDPH AGQFTSGFFP IMMFALPAAA
LAITHCARPQ RRKEVGGLML SVALTSFVTG ITEPIEYSFL FIAPALYAVH AVLTGVSMAV
TWGLGVHDGF SFSAGLIDYV INWDLATKPW AIIPIGLCFA AVYYAVFRFA ITRFDLKTPG
REPADEVEDT TRA
//
