ID   A0A176L368_9ACTN        Unreviewed;       601 AA.
AC   A0A176L368;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51192};
GN   ORFNames=A6P39_21050 {ECO:0000313|EMBL:OAA98917.1};
OS   Streptomyces sp. FXJ1.172.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=710705 {ECO:0000313|EMBL:OAA98917.1};
RN   [1] {ECO:0000313|EMBL:OAA98917.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FXJ1.172 {ECO:0000313|EMBL:OAA98917.1};
RA   Liu M., Liu N., Shang F., Huang Y.;
RT   "Activation and identification of NC-1, a novel cryptic cyclodepsipeptide
RT   from red soil-derived Streptomyces sp. FXJ1.172.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAA98917.1}.
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DR   EMBL; LWRP01000104; OAA98917.1; -; Genomic_DNA.
DR   RefSeq; WP_067048470.1; NZ_CP119133.1.
DR   AlphaFoldDB; A0A176L368; -.
DR   STRING; 710705.A6P39_21050; -.
DR   OrthoDB; 5165890at2; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd18785; SF2_C; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   4: Predicted;
FT   DOMAIN          42..199
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          409..451
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        409..447
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   601 AA;  66672 MW;  4C6D17B8FE46A47D CRC64;
     MTTTAASASS SHSHHLSPAF PGRAPWGTAS KLRAWQQGAM EKYVQEQPRD FLAVATPGAG
     KTTFALTLAS WLLHHHVVQQ VTVVAPTEHL KKQWAEAAAR IGIKLDPEYS AGPLGREYDG
     VAVTYAGVGV RPMLHRNRVE QRKTLVILDE IHHAGDSKSW GEACLEAFEP ATRRLALTGT
     PFRSDTNPIP FVTYEEGTDG IRRSSADYTY GYGNALADHV VRPVIFLSYS GNMRWRTKAG
     DEIAARLGEP MTKDAISQAW RTALDPRGEW MPSVLRAADQ RLTEVRKAIP DAGALVIASD
     QDSARAYAKL IREITGTKAT LVLSDDAGAS KRIDEFSESN DRWMVAVRMV SEGVDVPRLA
     VGVYATTIST PLFFAQAVGR FVRSRRRGET ASVFLPTVPD LLTFANEMEK ERDHALDKPK
     KEGEEDPYAE SEKEMEEANK QQDEDTGEQE QFSFEALESE AVFDRVLYDG AEFGMQAHPG
     SEEEQDYLGI PGLLEPDQVQ LLLQKRQARQ IAHSRKKPDA EADLLELPAE RRPVVSHKEM
     MELRKRLNTM VSAYVHQSGK PHGVIHTELR RVCGGPPSAE ATAGQLEQRI AKVQEWATRM
     K
//