ID   A0A176L6G9_9ACTN        Unreviewed;       353 AA.
AC   A0A176L6G9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=FAD-dependent oxidoreductase {ECO:0000313|EMBL:OAB00106.1};
DE   Flags: Fragment;
GN   ORFNames=A6P39_14020 {ECO:0000313|EMBL:OAB00106.1};
OS   Streptomyces sp. FXJ1.172.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=710705 {ECO:0000313|EMBL:OAB00106.1};
RN   [1] {ECO:0000313|EMBL:OAB00106.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FXJ1.172 {ECO:0000313|EMBL:OAB00106.1};
RA   Liu M., Liu N., Shang F., Huang Y.;
RT   "Activation and identification of NC-1, a novel cryptic cyclodepsipeptide
RT   from red soil-derived Streptomyces sp. FXJ1.172.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAB00106.1}.
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DR   EMBL; LWRP01000071; OAB00106.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A176L6G9; -.
DR   OrthoDB; 3217377at2; -.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   HAMAP; MF_00845; TetX_monooxygenase; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR043683; TetX_monooxygenase.
DR   PANTHER; PTHR46972; MONOOXYGENASE ASQM-RELATED; 1.
DR   PANTHER; PTHR46972:SF1; RHODANESE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01494; FAD_binding_3; 2.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          2..182
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
FT   DOMAIN          281..325
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:OAB00106.1"
SQ   SEQUENCE   353 AA;  37610 MW;  A18C449BFC0F30A4 CRC64;
     GGLTCARVLQ QHGRSVTVFE REASADARPQ GGSLDMHPDT GQAALRAAGL LDRFHALARP
     EGDEWRVLDF ATAALLAQQG PSANGGRPEI DRGQLRGLLL DSLTEGTVRW DRAVTGVTPL
     ADGTGRLLFG DGTAEDFDLV VGADGAWSRV RPALSPTVPG YTGVTFVETG FDDCDTRHPT
     LARLVGNGSM LAKGAGRTLV AQRNSNGHIR AYIALRAPKD WHEAAGVDLG DQRAVRTYLL
     RLFNDWDENL RYILRNSDHG FIHRSLFVLP APHTWDHVPG VTLLGDAAHL MPPVGLGANL
     AMLDGADLAH ALVTESSVDD AVRAYESIML PRSIEAATGS AKGLDNLVPA TAS
//