ID A0A176LAU9_9ACTN Unreviewed; 330 AA.
AC A0A176LAU9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=NADP-dependent oxidoreductase {ECO:0000313|EMBL:OAB01580.1};
GN ORFNames=A6P39_06250 {ECO:0000313|EMBL:OAB01580.1};
OS Streptomyces sp. FXJ1.172.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=710705 {ECO:0000313|EMBL:OAB01580.1};
RN [1] {ECO:0000313|EMBL:OAB01580.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FXJ1.172 {ECO:0000313|EMBL:OAB01580.1};
RA Liu M., Liu N., Shang F., Huang Y.;
RT "Activation and identification of NC-1, a novel cryptic cyclodepsipeptide
RT from red soil-derived Streptomyces sp. FXJ1.172.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAB01580.1}.
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DR EMBL; LWRP01000044; OAB01580.1; -; Genomic_DNA.
DR RefSeq; WP_067040568.1; NZ_CP119133.1.
DR AlphaFoldDB; A0A176LAU9; -.
DR STRING; 710705.A6P39_06250; -.
DR OrthoDB; 9805663at2; -.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 19..327
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 330 AA; 35413 MW; D56C35383AA6FF32 CRC64;
MTETALTVQQ TARPAGFPTA DHFRFAESPV PEPAPGTALV ENLLWSVDPY HREMMDAGFA
LNAPLEGRAL GKVVASRTPE LPEGEIVFHR QGWRTHAVVR PEEVRRLPHH PGVPLSAYLS
VLGGTGLTAY IALTRIARLR AGEDVFVSGA AGGVGTAAGR FARLLGAGRV IGSAGTPEKV
KYLTEQVRYD AAFDYRTAPV ADLLAEAAPT GIDVFVDNVG GDHLGAAIGA LRERGRVVRV
GTISQYNTPD APPVVFDHAD VVEKSLRIEG FLVKDHRDAQ DELYDFAVPH LRSGELAADE
TVIDGFERIV EAFLLMLRGG NTGKILVRAA
//
