ID   A0A176U791_9FIRM        Unreviewed;       717 AA.
AC   A0A176U791;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE            EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
GN   ORFNames=HMPREF2738_01342 {ECO:0000313|EMBL:OAD88633.1};
OS   Clostridiales bacterium KLE1615.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales.
OX   NCBI_TaxID=1715004 {ECO:0000313|EMBL:OAD88633.1, ECO:0000313|Proteomes:UP000077212};
RN   [1] {ECO:0000313|EMBL:OAD88633.1, ECO:0000313|Proteomes:UP000077212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KLE1615 {ECO:0000313|EMBL:OAD88633.1,
RC   ECO:0000313|Proteomes:UP000077212};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC         in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|RuleBase:RU000675};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAD88633.1}.
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DR   EMBL; LXPQ01000101; OAD88633.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A176U791; -.
DR   PATRIC; fig|1715004.3.peg.1328; -.
DR   Proteomes; UP000077212; Unassembled WGS sequence.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR019801; Glyco_hydro_35_CS.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077212}.
FT   DOMAIN          12..357
FT                   /note="Glycoside hydrolase 35 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01301"
SQ   SEQUENCE   717 AA;  80800 MW;  2822B30286D7E7A7 CRC64;
     MSTTYGFTNK YLTKDEKPWF PVMGEIHFSR YRADLWEESL RKMKAGGLSI ASVYVIWIHH
     EEEEGVFDFT GNRNLRGFLE AAKKVGISVF LRLGPWVHAE ARNGGFPDWL QKKQDEIDLR
     SNDPAYLAYV RRLWEKVYEQ AKGFLYQDGG PVIGMQIENE YGHVGGYNGE KGEQHMRTLT
     AMAREIGFDL PLCTATGWGG AATGGLLPVM GGYCEAPWDQ RITEIEPNTN YVFSHIRNDA
     LIASDHHVDD TVTFNEDDFP YLTAELGGGL QVTKHRRPIV SGNDVGAMSL TKLGSGVALL
     GYYMYHGGSN PDSKLSTLQE SRATGYLNDL PEINYDFNAP IRQYGTISDN YREIRLLAYF
     LQDFGADLAV LPADIDPDFV KPGDTHTLRV SVRHDDTHGY VFVNNYQRRL TMDDHKDVVL
     KGKTKGEPVC FPKTDIASGE YAFYPYNMKL KNAVLVSALA TPLCKLSCKD EDVYVFYGDK
     DPQFTWDGTP AKVLHLSRAD ALSAARVTLK DHQEYLVLSD DFVWEESGVL RVVGGEETII
     RTFPKLSKDV LPADFKEIAG EGELTVYKRS QAKNSANVQT SVSFVQSTKT PEELSGKLVN
     SCGQPETLKG DEKIYEISVQ YAKENRKGRN KGYDCILSFD YACESMELFV NGRKVNDYFY
     TGQKALFSLG YFDFPTKITA VLHPLHEGDH IYLQEWPKMD DKKACRIEAV TLTEQFS
//