ID   A0A176U919_9FIRM        Unreviewed;       489 AA.
AC   A0A176U919;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Putative aspartate ammonia-lyase {ECO:0000313|EMBL:OAD88774.1};
GN   ORFNames=HMPREF2738_01213 {ECO:0000313|EMBL:OAD88774.1};
OS   Clostridiales bacterium KLE1615.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales.
OX   NCBI_TaxID=1715004 {ECO:0000313|EMBL:OAD88774.1, ECO:0000313|Proteomes:UP000077212};
RN   [1] {ECO:0000313|EMBL:OAD88774.1, ECO:0000313|Proteomes:UP000077212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KLE1615 {ECO:0000313|EMBL:OAD88774.1,
RC   ECO:0000313|Proteomes:UP000077212};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAD88774.1}.
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DR   EMBL; LXPQ01000088; OAD88774.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A176U919; -.
DR   PATRIC; fig|1715004.3.peg.1202; -.
DR   Proteomes; UP000077212; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   CDD; cd01357; Aspartase; 1.
DR   Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR   Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR   Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR   InterPro; IPR024083; Fumarase/histidase_N.
DR   InterPro; IPR018951; Fumarase_C_C.
DR   InterPro; IPR020557; Fumarate_lyase_CS.
DR   InterPro; IPR000362; Fumarate_lyase_fam.
DR   InterPro; IPR022761; Fumarate_lyase_N.
DR   InterPro; IPR008948; L-Aspartase-like.
DR   PANTHER; PTHR42696; ASPARTATE AMMONIA-LYASE; 1.
DR   PANTHER; PTHR42696:SF2; ASPARTATE AMMONIA-LYASE; 1.
DR   Pfam; PF10415; FumaraseC_C; 1.
DR   Pfam; PF00206; Lyase_1; 1.
DR   PRINTS; PR00145; ARGSUCLYASE.
DR   PRINTS; PR00149; FUMRATELYASE.
DR   SUPFAM; SSF48557; L-aspartase-like; 1.
DR   PROSITE; PS00163; FUMARATE_LYASES; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:OAD88774.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077212}.
FT   DOMAIN          31..359
FT                   /note="Fumarate lyase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00206"
FT   DOMAIN          425..478
FT                   /note="Fumarase C C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10415"
SQ   SEQUENCE   489 AA;  53468 MW;  35781BB08DA166DF CRC64;
     MNEKVYKETE GMKDMTEQEM EFRVEKDSIG TKDVPENVYY GVQSLRAAEN FHITGLNMHP
     EIINSLAYIK KAAAITNCEA GLLDKKRTQA IVQACDEILE GKFREDFIVD PIQGGAGTSL
     NMNANEVIAN RAIEILGGKK GDYSVVNPND HVNCGQSTND VIPTAGKMTS LRLLKKLKKQ
     LLRLHSALEQ KADEFDGVIK MGRTQLQDAV PIRLGQEFKA YSVAILRDLN RMDKAMDEMR
     TLNMGGTAVG TGLNADESYL RRIVPNLSEI SGMDLVQAYD LIDATQNLDS FVAVSGAVKA
     CAVTLSKIAN DLRLMSSGPR AGFGEINLPA KQNGSSIMPG KVNPVIPEVV NQVAFNAIGN
     DMTITMAAEA GQLELNAFEP IIFYCLFQSI DTIAYAVNTF VDNCVIGITA NETRCRYFVE
     NSVGIITAIC PYVGYQKAAE IAKEAIKTGE SVRKLIIEKG LLTKEQMDEI MDPVQMTEPG
     ISGKTVNKI
//