ID   A0A176WJ83_MARPO        Unreviewed;       494 AA.
AC   A0A176WJ83;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=EamA domain-containing protein {ECO:0000259|Pfam:PF00892};
GN   ORFNames=AXG93_3105s1040 {ECO:0000313|EMBL:OAE33197.1};
OS   Marchantia polymorpha subsp. ruderalis.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Marchantiophyta;
OC   Marchantiopsida; Marchantiidae; Marchantiales; Marchantiaceae; Marchantia.
OX   NCBI_TaxID=1480154 {ECO:0000313|EMBL:OAE33197.1, ECO:0000313|Proteomes:UP000077202};
RN   [1] {ECO:0000313|EMBL:OAE33197.1, ECO:0000313|Proteomes:UP000077202}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Tak-1 and cv. Tak-2 {ECO:0000313|Proteomes:UP000077202};
RC   TISSUE=Whole gametophyte {ECO:0000313|EMBL:OAE33197.1};
RA   Honkanen S., Jones V.A., Morieri G., Champion C., Hetherington A.J.,
RA   Kelly S., Saint-Marcoux D., Proust H., Prescott H., Dolan L.;
RT   "Mechanisms controlling the formation of the plant cell surface in tip-
RT   growing cells are functionally conserved among land plants.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAE33197.1}.
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DR   EMBL; LVLJ01000678; OAE33197.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A176WJ83; -.
DR   OrthoDB; 1080641at2759; -.
DR   Proteomes; UP000077202; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.3730.20; -; 1.
DR   InterPro; IPR000620; EamA_dom.
DR   PANTHER; PTHR23051:SF0; SOLUTE CARRIER FAMILY 35 MEMBER F5; 1.
DR   PANTHER; PTHR23051; SOLUTE CARRIER FAMILY 35, MEMBER F5; 1.
DR   Pfam; PF00892; EamA; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077202};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        18..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        51..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        218..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        252..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        319..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          189..265
FT                   /note="EamA"
FT                   /evidence="ECO:0000259|Pfam:PF00892"
FT   REGION          116..153
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..153
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   494 AA;  54157 MW;  6F8F3BC8C3322E3C CRC64;
     MEEERSAAST PSSISWRWVW GVIYIILVAL IWIVASFVVQ SVVDSGVSPF LITYICNSLF
     VVYIPIVEGS EKLKSFMRRK GWSKTLNEKA RELCEKIPEA PQFVTNLPER QNLLENGREE
     GAAVPRTSEE EVSTPRNNIE DEHGSVEEGR SLEQEEDALL PIKTGTAVAV LEDGDLQQQR
     LQEADYQPWS RKRTALVGLT ICPFWFLAQL TFNLSLKYTT VTSNTILSTA SSLFTLLVSV
     KFLGEKFTWV KLVSVLLCMS GSIFVAVGDS WNGKAEYASN AVLGDVICLS SAMFYATYTA
     LIRVKIPDED DGNGKCSTAL VLGYIGLFNG LIFGPIALFL HFSGIEPFHR LTLTQFGLII
     GKGLIDNVLS DYLWARAVLL TTPTAATAGL TIQVPIAAVV DSVRGIVPSP LNVLGAIAVL
     IGFFGINQSA VSHEDMKDVK KVVHTDESNL TTVSPEIFRN IGTFAPASHW RLPKRLSCRK
     GSFGRIGRPA CALA
//