ID A0A177AVK9_9BILA Unreviewed; 537 AA.
AC A0A177AVK9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=A3Q56_06250 {ECO:0000313|EMBL:OAF66026.1};
OS Intoshia linei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mesozoa; Orthonectida;
OC Rhopaluridae; Intoshia.
OX NCBI_TaxID=1819745 {ECO:0000313|EMBL:OAF66026.1, ECO:0000313|Proteomes:UP000078046};
RN [1] {ECO:0000313|EMBL:OAF66026.1, ECO:0000313|Proteomes:UP000078046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Intl2013 {ECO:0000313|EMBL:OAF66026.1};
RC TISSUE=Whole animal {ECO:0000313|EMBL:OAF66026.1};
RA Mikhailov K.V., Slusarev G.S., Nikitin M.A., Logacheva M.D., Penin A.,
RA Aleoshin V., Panchin Y.V.;
RT "The genome of Intoshia linei affirms orthonectids as highly simplified
RT spiralians.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAF66026.1}.
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DR EMBL; LWCA01001060; OAF66026.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A177AVK9; -.
DR Proteomes; UP000078046; Unassembled WGS sequence.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF6; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000078046}.
FT DOMAIN 80..216
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 499..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..523
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 61443 MW; D6C3AFDF476AB4DC CRC64;
MNVINVKENN PIKRKSTIKQ IPAKKPKIEE STDTTTNILW TDKYRPTKMN KLVGQHGPKS
AANQLSEWLG QWRDQDTNDI PGAALLSGLP GLGKTTSALI VSKEMGFSPI ELNASDKRSK
KMLESGLAVS ISNKTITSFF KKKEKRQELD KNAIIIMDEV DGMAGNEDRG GVSLLIDLIK
KTTIPIICIC NDASLPKMRS LSKYCLHLKF NRYRVEQIKA HLMSICFKEN VSVESNALTN
MIEKSDRDIR QCINNLQIMA SQNKKLDFDL MYKYSNDSKK PTKLNAFDIA RYYITPMGSN
ANSIKIKLEH FFNEYDVVPL MVQENYIKVI SSNRSMSKLE ALSKAANSMA VGDMIFNQIR
SMNRWNLLPE YGFAGAYYPG ELIRGQLGFM DLRFPQWFGK NSSRNKNMRL IQQIIKHSCL
KCDSFTISSS PDSLFYYYLI IKKCLNNDFE EFFNFMQEYA FSREDVETIL DIASITSSFK
MDTKTKRTLT KKLKSVSRNL PYSTSEDVKK SKKTKLVKSE PETESEPESE DTEYDEY
//
