ID A0A177D676_ALTAL Unreviewed; 857 AA.
AC A0A177D676;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=DNA cross-link repair protein pso2/snm1 {ECO:0000313|EMBL:OAG14958.1};
GN ORFNames=CC77DRAFT_1025293 {ECO:0000313|EMBL:OAG14958.1};
OS Alternaria alternata (Alternaria rot fungus) (Torula alternata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Alternaria;
OC Alternaria sect. Alternaria; Alternaria alternata complex.
OX NCBI_TaxID=5599 {ECO:0000313|EMBL:OAG14958.1, ECO:0000313|Proteomes:UP000077248};
RN [1] {ECO:0000313|EMBL:OAG14958.1, ECO:0000313|Proteomes:UP000077248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRC1lrK2f {ECO:0000313|EMBL:OAG14958.1,
RC ECO:0000313|Proteomes:UP000077248};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC family. {ECO:0000256|ARBA:ARBA00010304}.
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DR EMBL; KV441496; OAG14958.1; -; Genomic_DNA.
DR RefSeq; XP_018380379.1; XM_018526043.1.
DR AlphaFoldDB; A0A177D676; -.
DR STRING; 5599.A0A177D676; -.
DR GeneID; 29111637; -.
DR KEGG; aalt:CC77DRAFT_1025293; -.
DR VEuPathDB; FungiDB:CC77DRAFT_1025293; -.
DR OMA; AQVHMHS; -.
DR OrthoDB; 23465at2759; -.
DR Proteomes; UP000077248; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR CDD; cd16273; SNM1A-1C-like_MBL-fold; 1.
DR Gene3D; 3.40.50.12650; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR011084; DRMBL.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240:SF6; DNA CROSS-LINK REPAIR 1A PROTEIN; 1.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR Pfam; PF07522; DRMBL; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000077248}.
FT DOMAIN 695..822
FT /note="DNA repair metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF07522"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..126
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..221
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..251
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 94556 MW; BA27F738524B9B50 CRC64;
MASKTATKKV APKPNTKALP PKKAIVQTTL TPADFAKKSP AGNGKKQKPA GTPNGNIMAF
FKKAEEINSR IFLQERGSNP TIVFDGDEDD VGWSDEKSNG VMTTDNDEER YNENGGSVKR
RKVSEEAVAL VPACSPPPPT DVESNTLDAL AADVPKQASK PRKKSGPFVD DSESEDDNVE
VPATTSGMAI RGQNDDSPIA KPTEGRLPAD SIEDHIPREL PPLKSESTSQ NGDEALDEYE
DLEDDDLLEG EEYDERRWMK EQQKLEMEEA GFEGDPDEFD APPLFPESGT SEPKQEEPNA
KDIPSCPICG NDLPGLSEQD VSVHVNACLD GNPIPLPVAK PKEENRLTTT SKAKAFKRPD
RPAKPGQANP FQLAKPSTQP SSAFSKLMAG HAEDAAWASA AAENNKSRGK PAYQRTCPFY
KIMPGFFIAV DAFRYGAVKG QNAYFLSHFH SDHYIGLTSS WKHGPIYCSK VTGNLVRQQL
RVDPKWVVDL DFEKKTEVPG TEGVHVTMIS ANHCPGSSLF LFEKELSKGK SSRLQRVLHC
GDFRACQEHI EHPLLRPDVL DAVSGKNRQQ KLDACYLDTT YLNPKYAFPP QKQVIQACAD
MCVSLSKSRA DDSDGWERMK RERAGQGMVQ FVRKDASIDN AGEPKSPERG RLLVVVGTYS
IGKERICTGI AKALGSKIFA PANKQRICKA LEDPELDALL TTDPRAAQVH MTPLFEIRAE
TLDDYLREYA DTFSRVVGFR PSGWNYRPPK GRFTESPQVQ TVLHSDNWKS TFAMKDLTPQ
AGSGSRASCF GVPYSEHSSF RELTMFCCAL HIDKIIPTVN VGSAKSREKM KAWCDRWAAD
KKKNGLFKLG EHGQGWS
//
