ID A0A177D976_ALTAL Unreviewed; 596 AA.
AC A0A177D976;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=MFS multidrug transporter-like protein {ECO:0000313|EMBL:OAG15479.1};
GN ORFNames=CC77DRAFT_444929 {ECO:0000313|EMBL:OAG15479.1};
OS Alternaria alternata (Alternaria rot fungus) (Torula alternata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Alternaria;
OC Alternaria sect. Alternaria; Alternaria alternata complex.
OX NCBI_TaxID=5599 {ECO:0000313|EMBL:OAG15479.1, ECO:0000313|Proteomes:UP000077248};
RN [1] {ECO:0000313|EMBL:OAG15479.1, ECO:0000313|Proteomes:UP000077248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRC1lrK2f {ECO:0000313|EMBL:OAG15479.1,
RC ECO:0000313|Proteomes:UP000077248};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KV441493; OAG15479.1; -; Genomic_DNA.
DR RefSeq; XP_018380900.1; XM_018531716.1.
DR AlphaFoldDB; A0A177D976; -.
DR GeneID; 29117310; -.
DR KEGG; aalt:CC77DRAFT_444929; -.
DR VEuPathDB; FungiDB:CC77DRAFT_444929; -.
DR OMA; DRWIWFV; -.
DR OrthoDB; 1934860at2759; -.
DR Proteomes; UP000077248; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR010573; MFS_Str1/Tri12-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23501:SF109; MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF06609; TRI12; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077248};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 70..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 561..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 70..514
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 596 AA; 64079 MW; D22466B25F7788C3 CRC64;
MKNMMRDHSD GSDVSDNSPT TSKPAFNHIE QIHTNEQVPG HTNYYEKDGL RTAGDGVDHE
ADVPMNFTRI MALVAMAFLW TGSQIPVYLF GGVPPYIYAD LGGADRWIWF VLANLLSLAA
ICPFVGSISD IVGRRWVAMI GASFLILGMI ICSTAHTMNT FIAGMVFSGV GAGINELTAL
AVTSELAPTS QRGKYVAILV FTIIPFCPSV LWAQLIASTS TGAWRWIGLW CGVWAFIGLV
LTAVFYHPPP RVNSVGMSRK ETLAQIDYVG GFLSVAGMIL FMMGMQWGGY QYKWSSAHVL
APLILGAAFI IAFILWEAYG AKHPMFPKRL RQEPRILGLT LVITFISGAN FFSILMFWPT
QAFNVYGHDP VGVGLRGLPV GFSILAGACI VLWLLSMLRG HNKELLIASS ILMTAGCGAL
AVGRVDNLAT LWGLLVLAGL GIGGIVVPAS IISTIICPDD LIATVAALTL AIRVIGGSIG
YCVYYNVFIS KFVPAATHYI GGVMVTQLNI TSPEIIGEAI TITGASLLPA LQELPGIKGV
PGAYEMVVYA GQLAYAEAYK YVYYVSIAFG GVSIIAACFL GDISKYMDDH VAVVMH
//
