ID A0A177DIN3_ALTAL Unreviewed; 2323 AA.
AC A0A177DIN3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=THO complex subunit 2 {ECO:0000256|ARBA:ARBA00019596};
GN ORFNames=CC77DRAFT_990433 {ECO:0000313|EMBL:OAG19623.1};
OS Alternaria alternata (Alternaria rot fungus) (Torula alternata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Alternaria;
OC Alternaria sect. Alternaria; Alternaria alternata complex.
OX NCBI_TaxID=5599 {ECO:0000313|EMBL:OAG19623.1, ECO:0000313|Proteomes:UP000077248};
RN [1] {ECO:0000313|EMBL:OAG19623.1, ECO:0000313|Proteomes:UP000077248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRC1lrK2f {ECO:0000313|EMBL:OAG19623.1,
RC ECO:0000313|Proteomes:UP000077248};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the THOC2 family.
CC {ECO:0000256|ARBA:ARBA00007857}.
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DR EMBL; KV441480; OAG19623.1; -; Genomic_DNA.
DR RefSeq; XP_018385044.1; XM_018536315.1.
DR STRING; 5599.A0A177DIN3; -.
DR GeneID; 29121909; -.
DR KEGG; aalt:CC77DRAFT_990433; -.
DR VEuPathDB; FungiDB:CC77DRAFT_990433; -.
DR OMA; QERWTCI; -.
DR OrthoDB; 179356at2759; -.
DR Proteomes; UP000077248; Unassembled WGS sequence.
DR GO; GO:0000347; C:THO complex; IEA:InterPro.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR InterPro; IPR040007; Tho2.
DR InterPro; IPR021418; THO_THOC2_C.
DR InterPro; IPR021726; THO_THOC2_N.
DR InterPro; IPR032302; THOC2_N.
DR PANTHER; PTHR21597:SF0; THO COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR21597; THO2 PROTEIN; 1.
DR Pfam; PF11262; Tho2; 1.
DR Pfam; PF11732; Thoc2; 1.
DR Pfam; PF16134; THOC2_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000077248}.
FT DOMAIN 132..859
FT /note="THO complex subunit 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16134"
FT DOMAIN 861..936
FT /note="THO complex subunitTHOC2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11732"
FT DOMAIN 1230..1537
FT /note="THO complex subunitTHOC2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11262"
FT REGION 1..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1156..1201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1553..2323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..120
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..607
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1167..1183
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1559..1576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1614..1649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1693..1712
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1718..1741
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1756..1781
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1796..1814
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1887..1960
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2064..2079
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2080..2096
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2169..2323
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2323 AA; 257060 MW; FC140AE7C1937314 CRC64;
MPPPPKRKRP ERTYSQDDDR SGRPSPHRPQ NLGFAHHQQQ QANSPRGGGG GGGGGGGRRQ
SRNNGRGGSS VPQSPNNASS HASPTAMSPP ANTFPLTRPS QATPTTPAPA PAPSQPSTPS
TPREVPESNE YLTPDRVARW NGEARDAVVK AAMAAQGTGD VLTLSVIFHE IIEASMDQLL
DAGELGSIVR DITSAPADEH VDSVSTFLDT LSSLTQDEGK QALVRQMLVA TDIDVSRMRA
ELENDLLKSL GLVRDSFSKM AVRKATHALY RQSNYNLLRE ETEGYSKLMT EYFTTVNSEP
PSQEVVGETW QRVNALIGAF DLDIGRVLDV TLDVFANLLV KHGRFFVKML RSSAWWPELR
GFDNIKWEEP EVPTLPLWAR PDAKQWYYTD EEKDEQLRLR ESRDCKFWQR VGELGDRAGI
QAFFELGGRR ITANNRQPDQ TLPAEGAPLS KQQAARKWAD EWMEQTKTLP PSGNDIAAQL
LGFKLQFYAS DVRDATDELP DNLMYLIALL IKIGFISILD LYPHLYPLEP DMGAHKERLL
KAKKEKEESE RGAVVNALTM AGALPDETPG PPAVSRLRDA DSRSKSDTGR STPAKSDEPA
DKKKALPEPK DQKFTLLKSL LCIGALPEAL FILGRHPWFL DVYPELLDLI FRLAHHSLTK
VYEESKPTSV EKSVIATKGS NNRGIMRPSD YVPRRTLRWA KPDRKDQDGG TDYKFYWEDW
VDNVPVCQEV DDVIKLCTSL LGLVGPECGK DSVLLTKIIR IGKKNLADDP SESNRKRWVN
FSATFIAPAI TFTGRNPGVI NEAWDLFKHF DTATRYTIYQ QWFNGMLKPV IKTAFKEVET
ETRKTLSRIS ATNTKEYGRK IAKISYASPG IVFRTTVKQL VNYPNMITAL VECSRYLTLL
GYDVLTWTLV TYLLNPDKGS QQDDGMLSAP WLKNIATFVG KAYARYHLMD PVPVLQLTTH
QLLTAEGELY MLDVLEQIVK SMGGISVSGS VSESVTLALC AGPALRTFTL QYRLADNRTH
AASSARRLVR CLKETGLGPQ ILIALAQHVE AYVHRDDQLE VPDKPVLFNV DKLRSVMLQY
LELLRTFLSV DDFDALFPPL VEMIADYHVE PDVAFTIARA GITAKANAFR AEQRSKLLSD
TQTNGDVVMS GVEESQAVNE AQDDATSAET SKAKEDVEMK DSVAAEGDSA SVTAARSDKP
FLPDVPNSEV EILANQLKEQ LPETFGNHPC VSYYVAFWQL SLTDVVVDVD GINQQYKDSI
ETLERQLPAP VPERRGYRPN VPKADSESVK ALKENIARIK DEQQVVTKNH AVTQESLKVE
LRRWFEGVPM MGPQCDVLHN ALLQDCFIPR SRISQEDAQY AFSMLIFMHS SGVPGFRMSR
LLDMLFNANR LTSIISMYTE AESSSFGRFL GGIMRELQVW QENKDDAFVK NAHGLEKNLP
GFGRSYDGDR NATSFFTYDQ FCMVLFKWHK ALAAALKTCL ESGNYMQMRN SINVLHALGT
NFPKVTSMGT ELKEMVVRLK EGEERQDLMR SLESVLGPIL KGEKFWQEDH VFRNVPAPTP
APGSTTNGSD KAATEKGKTP QPQDAKLDAA APAFKPKSET NGTPVRESNE NRSKHNSATP
APSSRDKPTP RTSDSRPSTP SQQDTGSGRP TPKPGPPMHH SSVPLRPDNR NTPGQNTPVG
RPPHALPTRP DPQPRNRSER PIIDRTPESA HGRYDNRGPP GDYGRLDRSV DAGRLREASP
GRRARPLPGG RTPERVPSAA EHREWSGRER DYDDRAMRGP PRDSRAPAVR PPTWDPHNPR
DMRDQRERSD PRGHATPTAM ESRRMPSTSS LANEYRRDGP PANAPYAAEQ NDRPSRLPAV
PIPAKEEPTV NPARAALINQ AEHAGGRHMP PRSDRDNRSE RDSRMNSPRH GDDRRGDDRR
VEERPPAGYH GRNDLPRDVR DERPQMPPSG GRDRRDDPGA SAPTGPRGGR NEAAAASRAS
REMFQPTPGP RAQDPNYGRL NQPSEPAPPS GPRSDRPHAP SQPSTPNAPT GPAASLPAGI
HPSRLVNIEG RAPSGPPLQT NVPNAPSGPR GNNRGPQGPV PSSPVGPRPP TGPGGPRNAG
NPLRAINNVL TGNAPGDRSN ERGAPPSNPP VRGRGATRAN GPIEGSGGMT SPMPPPALDS
TPNRMENQHP RSSRNDDVAS RMEGAPPEEG RSESRSHRHR SGRERSPDRS DRPREERSSR
NPPSDRPEGE RGSDRDRGGR EKRGGDRGSS HRERERDGES RSGREPRESS RRERGSRDDG
RASGRDERDR RSRGGGGSGG TDDGRKRGRD PQDQGHGETK RRR
//
