ID A0A177E2C7_ALTAL Unreviewed; 681 AA.
AC A0A177E2C7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Nucleolar complex-associated protein 3 {ECO:0000256|PIRNR:PIRNR028977};
GN ORFNames=AA0117_g2249 {ECO:0000313|EMBL:RYN81684.1}, CC77DRAFT_978721
GN {ECO:0000313|EMBL:OAG26127.1};
OS Alternaria alternata (Alternaria rot fungus) (Torula alternata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Alternaria;
OC Alternaria sect. Alternaria; Alternaria alternata complex.
OX NCBI_TaxID=5599 {ECO:0000313|EMBL:OAG26127.1, ECO:0000313|Proteomes:UP000077248};
RN [1] {ECO:0000313|EMBL:OAG26127.1, ECO:0000313|Proteomes:UP000077248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRC1lrK2f {ECO:0000313|EMBL:OAG26127.1,
RC ECO:0000313|Proteomes:UP000077248};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000291422}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FERA 1177 {ECO:0000313|Proteomes:UP000291422};
RA Armitage A.D., Cockerton H.M., Sreenivasaprasad S., Woodhall J., Lane C.,
RA Harrison R.J., Clarkson J.P.;
RT "Genomics, evolutionary history and diagnostics of the Alternaria alternata
RT species group including apple and Asian pear pathotypes.";
RL bioRxiv 0:0-0(2019).
RN [3] {ECO:0000313|EMBL:RYN81684.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FERA 1177 {ECO:0000313|EMBL:RYN81684.1};
RA Armitage A.D., Cockerton H.M., Sreenivasaprasad S., Woodhall J., Lane C.,
RA Harrison R.J., Clarkson J.P.;
RT "Genomics, evolutionary history and diagnostics of the Alternaria alternata
RT species group including apple and Asian pear pathotypes.";
RL J. ISSAAS 0:0-0(2019).
CC -!- FUNCTION: Required for synthesis of 60S ribosomal subunits and the
CC transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
CC {ECO:0000256|PIRNR:PIRNR028977}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|PIRNR:PIRNR028977}.
CC -!- SIMILARITY: Belongs to the CBF/MAK21 family.
CC {ECO:0000256|ARBA:ARBA00007797, ECO:0000256|PIRNR:PIRNR028977}.
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DR EMBL; KV441469; OAG26127.1; -; Genomic_DNA.
DR EMBL; PDXD01000002; RYN81684.1; -; Genomic_DNA.
DR RefSeq; XP_018391548.1; XM_018536012.1.
DR STRING; 5599.A0A177E2C7; -.
DR GeneID; 29121606; -.
DR KEGG; aalt:CC77DRAFT_978721; -.
DR VEuPathDB; FungiDB:CC77DRAFT_978721; -.
DR OMA; HYCPQVR; -.
DR OrthoDB; 24935at2759; -.
DR Proteomes; UP000077248; Unassembled WGS sequence.
DR Proteomes; UP000291422; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR005612; CCAAT-binding_factor.
DR InterPro; IPR011501; Noc3_N.
DR InterPro; IPR016903; Nucleolar_cplx-assoc_3.
DR PANTHER; PTHR14428; NUCLEOLAR COMPLEX PROTEIN 3; 1.
DR PANTHER; PTHR14428:SF5; NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG; 1.
DR Pfam; PF03914; CBF; 1.
DR Pfam; PF07540; NOC3p; 1.
DR PIRSF; PIRSF028977; Nucleolar_complex_p3; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000077248};
KW Ribosome biogenesis {ECO:0000256|PIRNR:PIRNR028977}.
FT DOMAIN 121..211
FT /note="Nucleolar complex-associated protein 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07540"
FT DOMAIN 480..668
FT /note="CCAAT-binding factor"
FT /evidence="ECO:0000259|Pfam:PF03914"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 44..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 362..389
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 681 AA; 76328 MW; 5E7832E88C9E397A CRC64;
MSRSVPVAKR RRLSPPEDGE RANGASEDHK AKFLKNAAKW DLEQDYETRP RKLKKQKENK
KLPVRTTEGW VAAPPNAQDI KEEESDSFLG SGSEDEAAEA SDVEEVEEQK PKISARQMIL
EAKEELARIA SLINEDPEEH IGALKTLQAL AESENFNVRK LALATQVSIF KDVIPGYRIR
PLSEEKMQEK ISKEVKKLRQ FEQKLVSSYE AHVKYLARLA KNSGSDKQHM ASLASVAVSC
ACNLLNSVPH FNFRSELIKI LVGKLSTRRV DADFVRCREA METLFENDED GNAALEAVTM
LTKMMKSRNY HFDESVLNTF LHLRLLSEFA QKASYHSVDK AEDPTVNGKK QKQKREFRTK
RLRKELKEKK AIEKEFKEAD AAVSHEERDR MQAETLKMVF VAYFRILKAR SPKLMGAVLE
GLARYAHLIN QDFFGDILEA LRDIIATAEL TAAAAVEEDE DASGEEDDNE APERNLTRES
LLCVITAFAL LEGQDGAKTA SALKLDLSYF ITHLYRTLHP VALNPDIELS SKSLHLPEPN
AAESHADTAK INVQTTIVLL IRSLSSVLLP ATSIRAVPPL RVAAFAKQLM SISMHLPEKS
CTAMLGLLNR VTKTHGKKVA PLWNTEERRG DGVFDALKPE IEGSNPFAGT IWEGEILRKH
FAPSVREAVS GVERNVLEAS R
//
