ID A0A177EAX1_9MICR Unreviewed; 152 AA.
AC A0A177EAX1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Transcription factor SPN1 {ECO:0000313|EMBL:OAG28948.1};
GN ORFNames=NEDG_01087 {ECO:0000313|EMBL:OAG28948.1};
OS Nematocida displodere.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nematocida.
OX NCBI_TaxID=1805483 {ECO:0000313|EMBL:OAG28948.1, ECO:0000313|Proteomes:UP000185944};
RN [1] {ECO:0000313|EMBL:OAG28948.1, ECO:0000313|Proteomes:UP000185944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JUm2807 {ECO:0000313|EMBL:OAG28948.1,
RC ECO:0000313|Proteomes:UP000185944};
RA Luallen R.J., Reinke A.W., Tong L., Botts M.R., Felix M.-A., Troemel E.R.;
RT "Discovery of a natural microsporidian pathogen with a broad tissue tropism
RT in Caenorhabditis elegans.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription factor involved in RNA polymerase II
CC transcription regulation. May function in both SPT15/TBP post-
CC recruitment and recruitment steps of transcription.
CC {ECO:0000256|ARBA:ARBA00037349}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the IWS1 family.
CC {ECO:0000256|ARBA:ARBA00037992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAG28948.1}.
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DR EMBL; LTDL01000042; OAG28948.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A177EAX1; -.
DR STRING; 1805483.A0A177EAX1; -.
DR EnsemblFungi; OAG28948; OAG28948; NEDG_01087.
DR VEuPathDB; MicrosporidiaDB:NEDG_01087; -.
DR OrthoDB; 12240at2759; -.
DR Proteomes; UP000185944; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR46010; PROTEIN IWS1 HOMOLOG; 1.
DR PANTHER; PTHR46010:SF1; PROTEIN IWS1 HOMOLOG; 1.
DR Pfam; PF08711; Med26; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000185944}.
FT DOMAIN 73..150
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
SQ SEQUENCE 152 AA; 17655 MW; 1D0B9F3BFEC7A0A3 CRC64;
MNEEKEQAET LIVYDTKYVK DLIEEIEAAA EEDQRLNQEG KPALHKLFLM DTIYNKLLNR
KIHLELLDSG ILGALRKWLE PLPNNSLPSD EVKKGIIDIL QHFHPMKEHL IESGIGKIIL
FYSKNPYEKK PIKRAAKQLV LKWIEVAAER DD
//
