ID A0A177ECD2_9MICR Unreviewed; 391 AA.
AC A0A177ECD2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Amino acid transporter transmembrane domain-containing protein {ECO:0000259|Pfam:PF01490};
GN ORFNames=NEDG_00738 {ECO:0000313|EMBL:OAG29605.1};
OS Nematocida displodere.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nematocida.
OX NCBI_TaxID=1805483 {ECO:0000313|EMBL:OAG29605.1, ECO:0000313|Proteomes:UP000185944};
RN [1] {ECO:0000313|EMBL:OAG29605.1, ECO:0000313|Proteomes:UP000185944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JUm2807 {ECO:0000313|EMBL:OAG29605.1,
RC ECO:0000313|Proteomes:UP000185944};
RA Luallen R.J., Reinke A.W., Tong L., Botts M.R., Felix M.-A., Troemel E.R.;
RT "Discovery of a natural microsporidian pathogen with a broad tissue tropism
RT in Caenorhabditis elegans.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC {ECO:0000256|ARBA:ARBA00008066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAG29605.1}.
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DR EMBL; LTDL01000040; OAG29605.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A177ECD2; -.
DR STRING; 1805483.A0A177ECD2; -.
DR EnsemblFungi; OAG29605; OAG29605; NEDG_00738.
DR VEuPathDB; MicrosporidiaDB:NEDG_00738; -.
DR OrthoDB; 5485318at2759; -.
DR Proteomes; UP000185944; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR22950:SF646; SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 10-RELATED; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185944};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..387
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
SQ SEQUENCE 391 AA; 42296 MW; 857BCA895CB22BFB CRC64;
MGHEILTGHF NLLKTIIGSG IVSFPSFFAV FGIVPTVVFS CISAVLAFAG LMMLCECASF
IGNSKGTFSS SLEDVLPGIA YFFNVIVFAK CFGVSISYLI ILRPLLEYLA EEAGVGLSGE
ELIVIYALLM IPVCALKDLK SFRFTSLLGI FGAYVCLGGS VYNLVVIAKK GNMPVVKFFA
NPNMGWIKKV GQFVFCFTCH QNIFSIRSGL SHPTRSKMAK VVGSSIVSAL VLYLTFGMTV
YYTYGNNIEP NVFMSFEANR VKTAVVLFYS LLITCSYPLQ VHPARDCLSE WLISATRVSS
AGKAGSLVRV VSTMIIVGAG LYISLLTISL DTIQSVVGGT ASAVMCNVIP AISLMYLQRK
KTSVEKVFVI LLLAYSVFSF AGVLSIFAKN K
//
