ID A0A177HEJ8_9ACTN Unreviewed; 538 AA.
AC A0A177HEJ8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=STSP_73360 {ECO:0000313|EMBL:OAH09483.1};
OS Streptomyces jeddahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1716141 {ECO:0000313|EMBL:OAH09483.1, ECO:0000313|Proteomes:UP000077381};
RN [1] {ECO:0000313|EMBL:OAH09483.1, ECO:0000313|Proteomes:UP000077381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G25(2015) {ECO:0000313|Proteomes:UP000077381};
RA Poehlein A., Roettig A., Hiessl S., Hauschild P., Schauer J., Madkour M.H.,
RA Al-Ansari A.M., Almakishah N.H., Steinbuechel A., Daniel R.;
RT "Genome sequence of Streptomyces sp. G25.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAH09483.1}.
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DR EMBL; LOHS01000200; OAH09483.1; -; Genomic_DNA.
DR RefSeq; WP_067285448.1; NZ_LOHS01000200.1.
DR AlphaFoldDB; A0A177HEJ8; -.
DR STRING; 1716141.STSP_73360; -.
DR PATRIC; fig|1716141.3.peg.7775; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000077381; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 2.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:OAH09483.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:OAH09483.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077381}.
FT DOMAIN 3..146
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 149..309
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT DOMAIN 398..503
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 307
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 538 AA; 58115 MW; 5A9885AC5E0DFDA5 CRC64;
MNAVIPRPAR QATATGGELP VAGPWRIRAA DGRLAAVAGT VRALLEPHLR DRLLPPDADG
GATGSGPATL TLALDEEPRA PHRTTVGISP RGAAEPVDES YRLTVTERGI TCRAVTPEGV
FRAAATAIQL LTTSAARILC QELTDAPHYA WRGLMVDPAR GYLTPGELRR VIDLAALYKL
NVLHLHLTDN EGWRLQLPAA PELTAPRGDG APREYYTTED YRALQEYAAE RFVTVVPEID
LPGHCAALRE AMPGLPAAPA PEGLAGRFPF VPPLDLADPG TRDVVAAILA DVCRLTAGPF
VHIGGDEAVG MTADGFALAI RELRALVRAS GRRPLAWQES SRAGIAPDDI AQFWVDVPMM
DLPDTEEELA DRPELLAAGH TLEFIKALKA FFAPADHDLA RIVQGGGRVL LSPQSHLYLD
RPYAHEVTPA HQVEAGARLG FRTYRSGGVR HTADWNPAAH AVPDERIAGV EATLFGESVG
GFDDLTTLLL PRMVSVAETA WTGRQPEWEG HRTRLARHAQ LWEERGLAYL ASTEIPWP
//
