ID   A0A177HT54_9ACTN        Unreviewed;       401 AA.
AC   A0A177HT54;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=N-acetylglucosamine repressor {ECO:0000313|EMBL:OAH13667.1};
GN   Name=nagC_6 {ECO:0000313|EMBL:OAH13667.1};
GN   ORFNames=STSP_30210 {ECO:0000313|EMBL:OAH13667.1};
OS   Streptomyces jeddahensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1716141 {ECO:0000313|EMBL:OAH13667.1, ECO:0000313|Proteomes:UP000077381};
RN   [1] {ECO:0000313|EMBL:OAH13667.1, ECO:0000313|Proteomes:UP000077381}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G25(2015) {ECO:0000313|Proteomes:UP000077381};
RA   Poehlein A., Roettig A., Hiessl S., Hauschild P., Schauer J., Madkour M.H.,
RA   Al-Ansari A.M., Almakishah N.H., Steinbuechel A., Daniel R.;
RT   "Genome sequence of Streptomyces sp. G25.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAH13667.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LOHS01000075; OAH13667.1; -; Genomic_DNA.
DR   RefSeq; WP_067277253.1; NZ_LOHS01000075.1.
DR   AlphaFoldDB; A0A177HT54; -.
DR   STRING; 1716141.STSP_30210; -.
DR   PATRIC; fig|1716141.3.peg.3176; -.
DR   OrthoDB; 4083144at2; -.
DR   Proteomes; UP000077381; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF12802; MarR_2; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01125; ROK; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000077381}.
FT   DOMAIN          21..66
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000259|Pfam:PF12802"
SQ   SEQUENCE   401 AA;  41206 MW;  8A14AD2DEC568405 CRC64;
     MYGKPGGSLR SLRRSNEEQV IALLIARGPL HRAELARQAG VSRTTVSTIV SELLARGLIV
     ESDEPDGDLD GRAGNRLLVN PRAAVVAGMN HTFDGVWVHL SDLGAREIAS SGAPLDPGTG
     PAERIEAGVS ILQRLLATAG VKRQQVIGVG VGVPGPIHRG TGIVGVSLPG QPWSHVHAAE
     ALQRALGLPV VVENNTRLEG VAEARWGAGR GVANLFYFGL SSGIGSGLIL DGRLYRGAVG
     AAGELGHVSV NVDGPACPCG NRGCLVLRAG LPAVLTALRP AFGQDTGLDE ILARTAAGER
     AGEEVFADVG TVVGQVLANL CNLLNPERIV VGGELSRAGE VLLAPMRDAV RRHALSLARD
     VDLVPAELGL GARVGALGGA ALVLSETPDL AAALNRMHAT V
//