ID A0A177HTH9_9ACTN Unreviewed; 285 AA.
AC A0A177HTH9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=biotin--[biotin carboxyl-carrier protein] ligase {ECO:0000256|ARBA:ARBA00024227};
DE EC=6.3.4.15 {ECO:0000256|ARBA:ARBA00024227};
GN Name=birA_2 {ECO:0000313|EMBL:OAH13889.1};
GN ORFNames=STSP_28670 {ECO:0000313|EMBL:OAH13889.1};
OS Streptomyces jeddahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1716141 {ECO:0000313|EMBL:OAH13889.1, ECO:0000313|Proteomes:UP000077381};
RN [1] {ECO:0000313|EMBL:OAH13889.1, ECO:0000313|Proteomes:UP000077381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G25(2015) {ECO:0000313|Proteomes:UP000077381};
RA Poehlein A., Roettig A., Hiessl S., Hauschild P., Schauer J., Madkour M.H.,
RA Al-Ansari A.M., Almakishah N.H., Steinbuechel A., Daniel R.;
RT "Genome sequence of Streptomyces sp. G25.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAH13889.1}.
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DR EMBL; LOHS01000072; OAH13889.1; -; Genomic_DNA.
DR RefSeq; WP_067276876.1; NZ_LOHS01000072.1.
DR AlphaFoldDB; A0A177HTH9; -.
DR STRING; 1716141.STSP_28670; -.
DR PATRIC; fig|1716141.3.peg.3015; -.
DR OrthoDB; 9807064at2; -.
DR Proteomes; UP000077381; Unassembled WGS sequence.
DR GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd16442; BPL; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR InterPro; IPR003142; BPL_C.
DR InterPro; IPR004143; BPL_LPL_catalytic.
DR InterPro; IPR008988; Transcriptional_repressor_C.
DR NCBIfam; TIGR00121; birA_ligase; 1.
DR PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR Pfam; PF02237; BPL_C; 1.
DR Pfam; PF03099; BPL_LplA_LipB; 1.
DR SUPFAM; SSF50037; C-terminal domain of transcriptional repressors; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE 4: Predicted;
KW Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OAH13889.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077381}.
FT DOMAIN 28..211
FT /note="BPL/LPL catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51733"
SQ SEQUENCE 285 AA; 29731 MW; BA1381789F26A44D CRC64;
MTPSDASDSR WSDLDRPPLN ATALRRALLR PGGLWTSLDV VASTGSTNTD LAARADALAE
GAVLVAEEQS SGRGRLDRQW TAPARSGLFF SVLLKPAEVP VERWGWLPLL AGVATATAVS
RAAGVDTALK WPNDLLVTVG GEERKTGGIL AERAGADGIV IGIGINVTLR AGELPVPTAG
SLALAGAATT DRDPLLRAVL RSLERWYIDW RAAGGDPAAC RLQETYAAGC ATLGRRVRAE
LPGDRTISGE AVAIDGDGRL VLATEDGVQQ PVGAGDIVHL RPARP
//
