ID   A0A177IGL3_9CORY        Unreviewed;       664 AA.
AC   A0A177IGL3;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   ORFNames=AYJ05_11735 {ECO:0000313|EMBL:OAH27969.1};
OS   Corynebacterium stationis.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1705 {ECO:0000313|EMBL:OAH27969.1, ECO:0000313|Proteomes:UP000076947};
RN   [1] {ECO:0000313|Proteomes:UP000076947}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GA-15 {ECO:0000313|Proteomes:UP000076947};
RA   Kaur G., Nair G.R., Mayilraj S.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAH27969.1}.
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DR   EMBL; LSTQ01000015; OAH27969.1; -; Genomic_DNA.
DR   RefSeq; WP_066839588.1; NZ_LSTQ01000015.1.
DR   AlphaFoldDB; A0A177IGL3; -.
DR   STRING; 1705.CA21670_10345; -.
DR   OrthoDB; 4318225at2; -.
DR   Proteomes; UP000076947; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR   PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076947};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           33..664
FT                   /note="VWFA domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008063940"
FT   TRANSMEM        637..658
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          47..233
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          579..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   664 AA;  71455 MW;  AAF8A133D5A57B6E CRC64;
     MVKVPRRTTF RQLVLMMAMA LAIGWTAWPA LAQDSSESAE AATEGSKIAL IMDASDSMNE
     EDVDGGTRLD AAKRASQQLV DSMPETAQLG MLAYGASESN APDNRERGCQ DIDVLAPVER
     INREELNAEI DALKAQGYTP MGNALKAAAD ELGSAGERSI ILVSDGIDTC APPPVCEVAE
     ELAGDGFDLA IHTVGFKADA AAQEELKCVS NVSGGTFVEA DNAEELGNQL EFLAQRDAQG
     YQVEGTEFEY ADTVEDAKWL DEGQYQTRVE VTETEDDVRY FRVAVPEGHH AHISVTGIPD
     RDASGQTSAG REGAVFVGVE DVSNHADGSD CRSEDLMTIA GGKIDLSNYA PTEPRVSTIE
     GDKPGNCDMN EWIVGHSFYG DDKRSLVGEE ISVEVNVTYE EIPPENQVQL EGDIGSLAQE
     EPEVKFSDAQ DIEAGTSFNN AVEVEPGTYA NSIVAGEVQY YRVPVEWGQV PQVALRNRVN
     ENIDHAWMTA QLLNPVRAVI ADNNTTSSSS DKTDVTQVVA DRPLRYNNRN ANWGGHPQSM
     AGDYFIAVSM SVPRQEESLD RIEQDYELAV DVTGAVDEGS AWRPSFEPGP EPSDTPPTFD
     ATSDEATETT TAAHADEDSD VANAAAEGNS ESGFTGLIWG TVGVLILGLI AIIGVLVFKL
     RKKQ
//