ID A0A177ISS5_9CORY Unreviewed; 440 AA.
AC A0A177ISS5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000256|ARBA:ARBA00040619};
GN ORFNames=AYJ05_10625 {ECO:0000313|EMBL:OAH31301.1};
OS Corynebacterium stationis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1705 {ECO:0000313|EMBL:OAH31301.1, ECO:0000313|Proteomes:UP000076947};
RN [1] {ECO:0000313|Proteomes:UP000076947}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GA-15 {ECO:0000313|Proteomes:UP000076947};
RA Kaur G., Nair G.R., Mayilraj S.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004155}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAH31301.1}.
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DR EMBL; LSTQ01000005; OAH31301.1; -; Genomic_DNA.
DR RefSeq; WP_066838073.1; NZ_LSTQ01000005.1.
DR AlphaFoldDB; A0A177ISS5; -.
DR STRING; 1705.CA21670_03850; -.
DR OrthoDB; 4332123at2; -.
DR Proteomes; UP000076947; Unassembled WGS sequence.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06174; MFS; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23512; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR23512:SF3; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076947};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..431
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 440 AA; 47101 MW; 8C144544D2A2A708 CRC64;
MSTPEFEKDP RPNPREVVTT KALTVWIAAL TVYVGAIFGR TSFGVAGVEA IARFDVDASR
IAVFASIQIG TYALAQVPTG ILIDRFGPRR LLVIGAIIMG IGQLILGLTT SYGVAIGARV
LIGAGDATAF LSVMRLLPFW FPLHRTPMFT AVTAAFGQLG QFLSAVPFLW LLHATGWTIA
FVSLGSVVIL IAIVAAISVA DSPESAGVYS EPSVEKDEPA LSIGQRMKLA LSSRATWQGF
FIHYAGLHAN LVFIMMWGVP MMTEAMGFSS AQAGTVLTIN SIAMIIVSPF HGRLSSLSGR
HRDISAFVLS LLHLLAWLWF FSSPSPRGLA VIIAMMILMA LSSPSSNYGF DQIRETLGRN
VVATATGLAN MGGFTAGMIA AQIFGIMLDK HSGGTAFVWG DFRYAALAVL VVWTIGLLGI
LVTRGGTRPR KIRMETVTED
//
