ID   A0A177IVX6_9CORY        Unreviewed;      1010 AA.
AC   A0A177IVX6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=AYJ05_01910 {ECO:0000313|EMBL:OAH32706.1};
OS   Corynebacterium stationis.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1705 {ECO:0000313|EMBL:OAH32706.1, ECO:0000313|Proteomes:UP000076947};
RN   [1] {ECO:0000313|Proteomes:UP000076947}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GA-15 {ECO:0000313|Proteomes:UP000076947};
RA   Kaur G., Nair G.R., Mayilraj S.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000256|ARBA:ARBA00009922}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00560}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAH32706.1}.
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DR   EMBL; LSTQ01000001; OAH32706.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A177IVX6; -.
DR   STRING; 1705.CA21670_09270; -.
DR   Proteomes; UP000076947; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.160; -; 1.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR038726; PDDEXK_AddAB-type.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF59; DNA HELICASE; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF12705; PDDEXK_1; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000076947}.
FT   DOMAIN          1..278
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   DOMAIN          233..530
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
SQ   SEQUENCE   1010 AA;  111614 MW;  8250ECDFE942E900 CRC64;
     MTSFLADTVL HQIELGQNPD SVLVVAASKE SGSRLREDIT TRLAAAQGQD FIAESAIVRS
     VHSLAFALLR QDSDEEIRLI TGAEQDAVIR ELLEGHVENN GGDWPAEIRP ALGYVGFARQ
     LRDFLLRAIE RQQTPDSLID LGTQHNQPMW TAAGHFLREY EQVMALSGIH SYSAAELVTQ
     VLLREHLTQS HPWETIVVDE AQLLDPTSGE LIRRLSKTAK LVVVGGDPNQ AVFAFRGATT
     DFLETFPAQH HLELSTPLRN PEPACVSIVD SERTQRDVLA DFIRRRHLDD GVAWKDIACI
     VRSSGDLGPI RRTLLAAGVP VHINPTDVVL SEQRLVAAIL LAVRALEEPL DNKDLEELLT
     GPIGGADPVG LRRLIRALRR WNPEARGMDM LREILASEEI EESLQEVLNN YETATLERII
     GILNSGREVL KHNGSPEEVL WAIWHKTELA NRLRNSSLRG GATGSQADRD LDAMMSLFDA
     AGDYSERRPG AELSAFINHI TEQVLPTGVR DRRTAVPDAV SILTAHGAVG REFNTVAIVG
     AQEGAWPALG ETGTIFAQEE LIDLVDLGID PNIPVNNIAD RLHEERRLFH VATTRHTSRM
     LLVAIDNPDG DEVAEPSRFI DEFANRAGRA RNIPEQLQRL ARQETFRKQL LAREMGLEPP
     ATVEIHEPDK EIDPLQVSVL SVSSFIAQMR TVVGNPQATE AARAQAARQL ARLAEAGVPG
     ADPAQWWATQ TISEEKPLNN NPRLSPSRIE ALLKCPLNAM LKDTADNTSD TYHLVRGNLA
     HAYMEALGRG ADEELARRET VEAFSQVQTS PSWKRAQERE EFERLLVRTN QWIQETRGVL
     ELVDVEVRVD VETEPGVRIR GYMDRLERAV GENGEHGGLR VIDLKTGAYK PSDEETSAHP
     QLMAYQLVLA HGELRQVDGF TRVVSSQQGE ERDGATLVYP GVDTKKIGTA EQARKEDEEL
     AEFAAALPPL LEELAGPRVT ARISSECDRC PLKPICPVQA EGKVTTDVNA
//