ID A0A177NFF9_9GAMM Unreviewed; 576 AA.
AC A0A177NFF9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=A1359_07140 {ECO:0000313|EMBL:OAI16796.1};
OS Methylomonas lenta.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomonas.
OX NCBI_TaxID=980561 {ECO:0000313|EMBL:OAI16796.1, ECO:0000313|Proteomes:UP000078476};
RN [1] {ECO:0000313|EMBL:OAI16796.1, ECO:0000313|Proteomes:UP000078476}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R-45370 {ECO:0000313|EMBL:OAI16796.1,
RC ECO:0000313|Proteomes:UP000078476};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAI16796.1}.
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DR EMBL; LUUI01000093; OAI16796.1; -; Genomic_DNA.
DR RefSeq; WP_066980825.1; NZ_LUUI01000093.1.
DR AlphaFoldDB; A0A177NFF9; -.
DR STRING; 980561.A1359_07140; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000078476; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00143; PP2Cc; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR PANTHER; PTHR43289:SF32; SERINE_THREONINE-PROTEIN KINASE PKAB; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51746; PPM_2; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OAI16796.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000078476};
KW Transferase {ECO:0000313|EMBL:OAI16796.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 553..572
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..239
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT DOMAIN 272..540
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 576 AA; 65345 MW; 013EC93DED245BF9 CRC64;
MPSQLKVSVG QHSDKGRKSI NQDFYGVYSP KEPLLTSKGI AIALADGISS SAVSQFASQA
AVTGFLEDYF CTSEAWSVRK SAQRVVMATN SWLHSQTRQS QYRYDKDKGY VCTFSAMVIK
STTAHIFHVG DARIYQLHGN ALEQLTTDHR FWVSQDKSHL SRALGIDQQV EIDYQALPLQ
TDDIFVCATD GVYEYVKAEF IIKTIQQNAN DLDKAAQVIV DEAFQQGSID NLTVQIIRVD
ELPSHDVTEI YQQLTELTFP PPLEARMDFD GYKIIRQVHA SSRSHVYLAL DVETSTQVII
KTPSIDLRGD PAYLERFLME EWIARRINSA HVLKPCWQTR KRHYLYIVTE FIDGQTLSQW
MTDNPRPELE TVRGIVEQIA KGLRAFHRLE MLHQDLRPNN IMIDSTGTLK IIDFGSTRVA
GIMEITTPIE QHDLLGTAQY TAPEYFLGES GTTRSDLFSL GVITYQMLTG KLPYGAEVAK
ASTKVAQNRL IYHSVLDDRH EIPAWVDDAI RKALQPNPYK RYQELSEFIF DLRHPNQVFL
TKTRPPLMER NPLVFWKSVS LILAAIVVAL LIKPVG
//
