ID A0A177NSY5_9GAMM Unreviewed; 329 AA.
AC A0A177NSY5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase (Inverting) {ECO:0000313|EMBL:OAI21031.1};
GN ORFNames=A1359_02455 {ECO:0000313|EMBL:OAI21031.1};
OS Methylomonas lenta.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomonas.
OX NCBI_TaxID=980561 {ECO:0000313|EMBL:OAI21031.1, ECO:0000313|Proteomes:UP000078476};
RN [1] {ECO:0000313|EMBL:OAI21031.1, ECO:0000313|Proteomes:UP000078476}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R-45370 {ECO:0000313|EMBL:OAI21031.1,
RC ECO:0000313|Proteomes:UP000078476};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-alpha-D-glucose = UDP-alpha-D-galactose;
CC Xref=Rhea:RHEA:22168, ChEBI:CHEBI:58885, ChEBI:CHEBI:66914;
CC EC=5.1.3.2; Evidence={ECO:0000256|ARBA:ARBA00000083};
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAI21031.1}.
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DR EMBL; LUUI01000022; OAI21031.1; -; Genomic_DNA.
DR RefSeq; WP_066976885.1; NZ_LUUI01000022.1.
DR AlphaFoldDB; A0A177NSY5; -.
DR STRING; 980561.A1359_02455; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000078476; Unassembled WGS sequence.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR InterPro; IPR020025; PseB.
DR NCBIfam; TIGR03589; PseB; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000078476}.
FT DOMAIN 7..277
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 329 AA; 36624 MW; DCBA84C0046DD204 CRC64;
MLNGKNILIT GGTGSFGKKC TKLILERYSP KRLVIFSRDE LKQYEMRQVF NQKCMRYFLG
DVRDQSRLKR GLEDIDVVIH AAALKQVPAA EYNPFECIKT NVLGAQNLIE ACLDTGVQRV
VALSTDKAAA PINLYGATKL CSDKLFVAAN NIAGSRDIRF SVVRYGNVMG SRGSVIPFFL
GQRKIGILPI TDPEMTRFNI SLREGVEMVL WAIENAWGGE VLVPKIPSYR IIDLAMAIGP
ECEHKIIGVR PGEKIHEEMI TESDSFNTVD LGPYFAILPA GAKYNMKNYC ARTNAQKVEP
GFRYDSGSNE HFLSVDELRT LIDSFVADA
//
