ID   A0A177QQA6_9BACT        Unreviewed;       468 AA.
AC   A0A177QQA6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Tyrosine phenol-lyase {ECO:0000313|EMBL:OAI49851.1};
GN   ORFNames=AYO43_00290 {ECO:0000313|EMBL:OAI49851.1};
OS   Nitrospira sp. SCGC AG-212-E16.
OC   Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC   Nitrospira.
OX   NCBI_TaxID=1799664 {ECO:0000313|EMBL:OAI49851.1, ECO:0000313|Proteomes:UP000078320};
RN   [1] {ECO:0000313|Proteomes:UP000078320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCGC AG-212-E16 {ECO:0000313|Proteomes:UP000078320};
RA   Choi J., Stepanauskas R., Howe A.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR611166-50};
CC   -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC       {ECO:0000256|ARBA:ARBA00009721}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAI49851.1}.
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DR   EMBL; LSTC01000001; OAI49851.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A177QQA6; -.
DR   STRING; 1799664.AYO43_00290; -.
DR   Proteomes; UP000078320; Unassembled WGS sequence.
DR   GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR   GO; GO:0009072; P:aromatic amino acid metabolic process; IEA:InterPro.
DR   CDD; cd00617; Tnase_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR011166; Beta-eliminating_lyase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   InterPro; IPR018176; Tryptophanase_CS.
DR   PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   PIRSF; PIRSF001386; Trpase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00853; BETA_ELIM_LYASE; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:OAI49851.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR611166-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078320}.
FT   DOMAIN          46..423
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
FT   MOD_RES         257
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR611166-50"
SQ   SEQUENCE   468 AA;  52971 MW;  D418712DF30A1987 CRC64;
     MKFPSEPFKI KVVEPIRRTT YEERDRLLRE AGYNLFHVPA ESVYVDLLTD SGTSAMSDNQ
     WAGLMLGDES YAGSRNYYHL EETVRSIFGY KHVIPTHQGR MAENLLFSTV VKPGMCVPNN
     IHFDTTRANV EHQGAQALDV VIKEAYDPHC ELPFKGNMDV VRLEETINRV GRNRIPLAML
     TVTNNSGGGQ PVSMDNIRQT RALLNRYRIP LFFDACRFAE NCFFVKEREP GYASKSILDI
     ARELFSYGDG CIMSAKKDGL VNIGGFLSLN HDQWAQDITN MLILVEGFPT YGGLAGRDLE
     AMARGLREGL DEDYLSFRVG QVRYLGELLD QAGVPILKPI GGHAVYLNAK EFLPHIQQAQ
     FPAQALVAAL YREYGIRGVE IGTVMFGKTD SETGRTIHPE LEMVRLAIPR RVYTNMQITY
     VAESIIELYR RRERIHGLAL TYEAPVLRHF TARFEELEER PLVQHAAS
//